Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy

Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy

Myotonic dystrophy type 1 (DM1) and 2 (DM2) are autosomal dominant degenerative neuromuscular disorders characterized by progressive skeletal muscle weakness, atrophy, and myotonia with progeroid features. Although both DM1 and DM2 are characterized by skeletal muscle dysfunction and also share othe...

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Bibliographic Details
Main Authors: Laurène M. André, C. Rosanne M. Ausems, Derick G. Wansink, Bé Wieringa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neurology
Subjects:
myotonic dystrophy
myogenesis
mesoangioblast
myoblast
muscle stem cell
pericyte
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00368/full

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