Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

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Leishmaniasis is a public health issue. It is among the top five parasitic illnesses worldwide and is one of the most neglected diseases. The current treatment disease includes limitations of toxicity, variable efficacy, high costs and inconvenient doses and treatment schedules. LASSBio-1736 was des...

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Main Authors: Aline Cavalcanti de Queiroz, Gisele Barbosa, Victória Regina Thomaz de Oliveira, Hélio de Mattos Alves, Marina Amaral Alves, Vanessa Carregaro, João Santana da Silva, Eliezer Jesus Barreiro, Magna Suzana Alexandre-Moreira, Lidia Moreira Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170106/?tool=EBI

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