Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study
Abstract Background Coronary slow flow phenomenon (CSFP) involves the delayed opacification of the coronary distal vessel, in the absence of an obstructive lesion in the epicardial coronary artery during angiography. Since the link between left atrial (LA) function and decreased left ventricular fun...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-02-01
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| Series: | Cardiovascular Ultrasound |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12947-020-00189-z |
| _version_ | 1818610156704890880 |
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| author | Jun Li Yonghuai Wang Cuiting Zhao Qing Zhu Guangyuan Li Jun Yang Dalin Jia Chunyan Ma |
| author_facet | Jun Li Yonghuai Wang Cuiting Zhao Qing Zhu Guangyuan Li Jun Yang Dalin Jia Chunyan Ma |
| author_sort | Jun Li |
| collection | DOAJ |
| description | Abstract Background Coronary slow flow phenomenon (CSFP) involves the delayed opacification of the coronary distal vessel, in the absence of an obstructive lesion in the epicardial coronary artery during angiography. Since the link between left atrial (LA) function and decreased left ventricular function is still unclear, we evaluated LA function using real-time three-dimensional echocardiography (RT3DE) in patients with CSFP, and subsequently determined the incremental value of RT3DE. Methods This study enrolled 60 patients with CSFP and 45 control subjects. CSFP was diagnosed based on thrombolysis in myocardial infarction frame count (TFC). The LA phasic volume and function was evaluated by both two-dimensional echocardiography (2DE) and RT3DE. Results The LA maximal volume (Volmax), pre-systolic volume (Volp), and minimal volume (Volmin) increased, but LA total and active ejection fraction decreased in patients with CSFP. Based on our results, Volmax, Volp, Volmin, and LA total and active ejection fraction correlated with TFC, and with the number of arteries involved. The LA total ejection fraction by RT3DE was the only independent predictor for CSFP (odds ratio, 0.64 [95% confidence interval, 0.49–0.83]; P = 0.001). Also, the LA total ejection fraction by RT3DE demonstrated good predictive power for CSFP, with a cut-off value of 54.15% (area under curve, 0.85; sensitivity, 84%; specificity, 83%). Conclusions The LA reservoir and contractile function decreased in the patients with CSFP and correlated with coronary flow rate and with the number of arteries involved. The LA total ejection fraction by RT3DE can independently predict CSFP, and RT3DE demonstrated incremental value for evaluating LA phasic function in the patients with CSFP compared to 2DE. |
| first_indexed | 2024-12-16T15:09:57Z |
| format | Article |
| id | doaj.art-7a9dd0224a10455e9b3a4eeda31eae57 |
| institution | Directory Open Access Journal |
| issn | 1476-7120 |
| language | English |
| last_indexed | 2024-12-16T15:09:57Z |
| publishDate | 2020-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Cardiovascular Ultrasound |
| spelling | doaj.art-7a9dd0224a10455e9b3a4eeda31eae572022-12-21T22:27:00ZengBMCCardiovascular Ultrasound1476-71202020-02-0118111010.1186/s12947-020-00189-zIncremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control studyJun Li0Yonghuai Wang1Cuiting Zhao2Qing Zhu3Guangyuan Li4Jun Yang5Dalin Jia6Chunyan Ma7Department of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityDepartment of Cardiology, The First Hospital of China Medical UniversityDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical UniversityAbstract Background Coronary slow flow phenomenon (CSFP) involves the delayed opacification of the coronary distal vessel, in the absence of an obstructive lesion in the epicardial coronary artery during angiography. Since the link between left atrial (LA) function and decreased left ventricular function is still unclear, we evaluated LA function using real-time three-dimensional echocardiography (RT3DE) in patients with CSFP, and subsequently determined the incremental value of RT3DE. Methods This study enrolled 60 patients with CSFP and 45 control subjects. CSFP was diagnosed based on thrombolysis in myocardial infarction frame count (TFC). The LA phasic volume and function was evaluated by both two-dimensional echocardiography (2DE) and RT3DE. Results The LA maximal volume (Volmax), pre-systolic volume (Volp), and minimal volume (Volmin) increased, but LA total and active ejection fraction decreased in patients with CSFP. Based on our results, Volmax, Volp, Volmin, and LA total and active ejection fraction correlated with TFC, and with the number of arteries involved. The LA total ejection fraction by RT3DE was the only independent predictor for CSFP (odds ratio, 0.64 [95% confidence interval, 0.49–0.83]; P = 0.001). Also, the LA total ejection fraction by RT3DE demonstrated good predictive power for CSFP, with a cut-off value of 54.15% (area under curve, 0.85; sensitivity, 84%; specificity, 83%). Conclusions The LA reservoir and contractile function decreased in the patients with CSFP and correlated with coronary flow rate and with the number of arteries involved. The LA total ejection fraction by RT3DE can independently predict CSFP, and RT3DE demonstrated incremental value for evaluating LA phasic function in the patients with CSFP compared to 2DE.https://doi.org/10.1186/s12947-020-00189-zCoronary slow flow phenomenonLeft atrialThree-dimensionalEchocardiography |
| spellingShingle | Jun Li Yonghuai Wang Cuiting Zhao Qing Zhu Guangyuan Li Jun Yang Dalin Jia Chunyan Ma Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study Cardiovascular Ultrasound Coronary slow flow phenomenon Left atrial Three-dimensional Echocardiography |
| title | Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study |
| title_full | Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study |
| title_fullStr | Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study |
| title_full_unstemmed | Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study |
| title_short | Incremental value of three-dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon: a case control study |
| title_sort | incremental value of three dimensional echocardiography for evaluating left atrial function in patients with coronary slow flow phenomenon a case control study |
| topic | Coronary slow flow phenomenon Left atrial Three-dimensional Echocardiography |
| url | https://doi.org/10.1186/s12947-020-00189-z |
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