Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy
We performed 99mTc-ethyl cysteinate dimer brain single-photon emission computed tomography before and after administering methyl-phenidate, for four weeks, to narcolepsy patients with cataplexy. Cerebral blood flow increased in the bilateral cingulate gyri and both thalami with methylphenidate treat...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Sleep Medicine
2010-11-01
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| Series: | Sleep Medicine Research |
| Subjects: | |
| Online Access: | http://www.sleepmedres.org/upload/pdf/smr-1-1-30.pdf |
| _version_ | 1811255120958062592 |
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| author | Eun Yeon Joo Woo Suk Tae Seung Bong Hong |
| author_facet | Eun Yeon Joo Woo Suk Tae Seung Bong Hong |
| author_sort | Eun Yeon Joo |
| collection | DOAJ |
| description | We performed 99mTc-ethyl cysteinate dimer brain single-photon emission computed tomography before and after administering methyl-phenidate, for four weeks, to narcolepsy patients with cataplexy. Cerebral blood flow increased in the bilateral cingulate gyri and both thalami with methylphenidate treatment as compared to pre-methylphenidate treatment. methylphenidate treatment also produced an regional cerebral blood flow increase in the bilateral nucleus accumbens, cingulate gyri, superior frontal gyri, and bilateral amygdalo-hippocampi and parahippocampal gyri as compared to pre-methylphenidate treatment. Moreover, no brain region showed a significant regional cerebral blood flow decrease after methylphenidate treatment. |
| first_indexed | 2024-04-12T17:17:52Z |
| format | Article |
| id | doaj.art-7a9febfe32eb4a33a210d73e1f4ef1c0 |
| institution | Directory Open Access Journal |
| issn | 2093-9175 2233-8853 |
| language | English |
| last_indexed | 2024-04-12T17:17:52Z |
| publishDate | 2010-11-01 |
| publisher | Korean Society of Sleep Medicine |
| record_format | Article |
| series | Sleep Medicine Research |
| spelling | doaj.art-7a9febfe32eb4a33a210d73e1f4ef1c02022-12-22T03:23:34ZengKorean Society of Sleep MedicineSleep Medicine Research2093-91752233-88532010-11-0111303110.17241/smr.2010.1.1.307Methylphenidate’s Effect on Cerebral Blood Flow in Patients with NarcolepsyEun Yeon Joo0Woo Suk Tae1Seung Bong Hong2 Department of Neurology, Sleep Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Neuroscience Research Institute, Kangwon National University College of Medicine, Chuncheon, Korea Department of Neurology, Sleep Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, KoreaWe performed 99mTc-ethyl cysteinate dimer brain single-photon emission computed tomography before and after administering methyl-phenidate, for four weeks, to narcolepsy patients with cataplexy. Cerebral blood flow increased in the bilateral cingulate gyri and both thalami with methylphenidate treatment as compared to pre-methylphenidate treatment. methylphenidate treatment also produced an regional cerebral blood flow increase in the bilateral nucleus accumbens, cingulate gyri, superior frontal gyri, and bilateral amygdalo-hippocampi and parahippocampal gyri as compared to pre-methylphenidate treatment. Moreover, no brain region showed a significant regional cerebral blood flow decrease after methylphenidate treatment.http://www.sleepmedres.org/upload/pdf/smr-1-1-30.pdfNarcolepsyMethylphenidateCerebral blood flow |
| spellingShingle | Eun Yeon Joo Woo Suk Tae Seung Bong Hong Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy Sleep Medicine Research Narcolepsy Methylphenidate Cerebral blood flow |
| title | Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy |
| title_full | Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy |
| title_fullStr | Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy |
| title_full_unstemmed | Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy |
| title_short | Methylphenidate’s Effect on Cerebral Blood Flow in Patients with Narcolepsy |
| title_sort | methylphenidate s effect on cerebral blood flow in patients with narcolepsy |
| topic | Narcolepsy Methylphenidate Cerebral blood flow |
| url | http://www.sleepmedres.org/upload/pdf/smr-1-1-30.pdf |
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