Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE co...
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Format: | Article |
Language: | English |
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MDPI AG
2022-04-01
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Series: | Antioxidants |
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Online Access: | https://www.mdpi.com/2076-3921/11/4/790 |
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author | Agnieszka Ścibior |
author_facet | Agnieszka Ścibior |
author_sort | Agnieszka Ścibior |
collection | DOAJ |
description | The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action. |
first_indexed | 2024-03-09T11:14:02Z |
format | Article |
id | doaj.art-7aa0fe06b58c4c868e2d52a947ca9350 |
institution | Directory Open Access Journal |
issn | 2076-3921 |
language | English |
last_indexed | 2024-03-09T11:14:02Z |
publishDate | 2022-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Antioxidants |
spelling | doaj.art-7aa0fe06b58c4c868e2d52a947ca93502023-12-01T00:36:57ZengMDPI AGAntioxidants2076-39212022-04-0111479010.3390/antiox11040790Overview of Research on Vanadium-Quercetin Complexes with a Historical OutlineAgnieszka Ścibior0Laboratory of Oxidative Stress, Centre for Interdisciplinary Research, The John Paul II Catholic University of Lublin, 20-708 Lublin, PolandThe present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action.https://www.mdpi.com/2076-3921/11/4/790vanadiumquercetinvanadium-quercetin complexesin vitro/in vivo studiesantidiabetic/antitumoral activityantioxidant potential |
spellingShingle | Agnieszka Ścibior Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline Antioxidants vanadium quercetin vanadium-quercetin complexes in vitro/in vivo studies antidiabetic/antitumoral activity antioxidant potential |
title | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_full | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_fullStr | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_full_unstemmed | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_short | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_sort | overview of research on vanadium quercetin complexes with a historical outline |
topic | vanadium quercetin vanadium-quercetin complexes in vitro/in vivo studies antidiabetic/antitumoral activity antioxidant potential |
url | https://www.mdpi.com/2076-3921/11/4/790 |
work_keys_str_mv | AT agnieszkascibior overviewofresearchonvanadiumquercetincomplexeswithahistoricaloutline |