Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline

The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE co...

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Main Author: Agnieszka Ścibior
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/4/790
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author Agnieszka Ścibior
author_facet Agnieszka Ścibior
author_sort Agnieszka Ścibior
collection DOAJ
description The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action.
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spelling doaj.art-7aa0fe06b58c4c868e2d52a947ca93502023-12-01T00:36:57ZengMDPI AGAntioxidants2076-39212022-04-0111479010.3390/antiox11040790Overview of Research on Vanadium-Quercetin Complexes with a Historical OutlineAgnieszka Ścibior0Laboratory of Oxidative Stress, Centre for Interdisciplinary Research, The John Paul II Catholic University of Lublin, 20-708 Lublin, PolandThe present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action.https://www.mdpi.com/2076-3921/11/4/790vanadiumquercetinvanadium-quercetin complexesin vitro/in vivo studiesantidiabetic/antitumoral activityantioxidant potential
spellingShingle Agnieszka Ścibior
Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
Antioxidants
vanadium
quercetin
vanadium-quercetin complexes
in vitro/in vivo studies
antidiabetic/antitumoral activity
antioxidant potential
title Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_full Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_fullStr Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_full_unstemmed Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_short Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_sort overview of research on vanadium quercetin complexes with a historical outline
topic vanadium
quercetin
vanadium-quercetin complexes
in vitro/in vivo studies
antidiabetic/antitumoral activity
antioxidant potential
url https://www.mdpi.com/2076-3921/11/4/790
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