Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis

Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis

<p>Abstract</p> <p>Background</p> <p>Recent data have suggested a relationship between acute arthritic pain and acid sensing ion channel 3 (ASIC3) on primary afferent fibers innervating joints. The purpose of this study was to clarify the role of ASIC3 in a rat model of...

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Bibliographic Details
Main Authors: Izumi Masashi, Ikeuchi Masahiko, Ji Qinghui, Tani Toshikazu
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Biomedical Science
Subjects:
Osteoarthritis
Acid sensing ion channel (ASIC)
Pain
APETx2
Joint
Inflammation
Online Access:http://www.jbiomedsci.com/content/19/1/77

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