-induced hematogenous disseminated severe pneumonia: a case report
Porphyromonas gingivalis , a gram-negative oral anaerobe among more than more than 500 bacterial species that colonizing the oral cavity, is involved in the pathogenesis and prototypic polybacterial consortium of periodontitis. It is mainly found in oral infections and rarely present in other organ...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-03-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231213760 |
| _version_ | 1797262247202914304 |
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| author | Zhou Yuanjun Cai Yan Zhang Qingyan Xiong Feng |
| author_facet | Zhou Yuanjun Cai Yan Zhang Qingyan Xiong Feng |
| author_sort | Zhou Yuanjun |
| collection | DOAJ |
| description | Porphyromonas gingivalis , a gram-negative oral anaerobe among more than more than 500 bacterial species that colonizing the oral cavity, is involved in the pathogenesis and prototypic polybacterial consortium of periodontitis. It is mainly found in oral infections and rarely present in other organ diseases. Here, we describe a 43-year-old man with underlying diabetes who developed hematogenous disseminated severe pneumonia after P. gingivalis had invaded the blood. Next-generation sequencing of early alveolar lavage fluid and blood samples confirmed the diagnosis. The patient’s lung infection improved after targeted antimicrobial treatment. He was successfully weaned from ventilatory support and transferred to the general ward. This case illustrates bacterial entry into the bloodstream of a patient with diabetes who had periodontal disease but did not maintain oral hygiene, leading to severe pneumonia. Periodontal disease is often ignored by the public, and it is difficult for critical care physicians to link severe pneumonia with periodontal disease. Thus, this case represents an important warning to critical care clinicians. |
| first_indexed | 2024-04-24T23:54:04Z |
| format | Article |
| id | doaj.art-7aa4d26655784dc781664a1f4637bf9a |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-24T23:54:04Z |
| publishDate | 2024-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-7aa4d26655784dc781664a1f4637bf9a2024-03-14T15:03:19ZengSAGE PublishingJournal of International Medical Research1473-23002024-03-015210.1177/03000605231213760-induced hematogenous disseminated severe pneumonia: a case reportZhou YuanjunCai YanZhang QingyanXiong FengPorphyromonas gingivalis , a gram-negative oral anaerobe among more than more than 500 bacterial species that colonizing the oral cavity, is involved in the pathogenesis and prototypic polybacterial consortium of periodontitis. It is mainly found in oral infections and rarely present in other organ diseases. Here, we describe a 43-year-old man with underlying diabetes who developed hematogenous disseminated severe pneumonia after P. gingivalis had invaded the blood. Next-generation sequencing of early alveolar lavage fluid and blood samples confirmed the diagnosis. The patient’s lung infection improved after targeted antimicrobial treatment. He was successfully weaned from ventilatory support and transferred to the general ward. This case illustrates bacterial entry into the bloodstream of a patient with diabetes who had periodontal disease but did not maintain oral hygiene, leading to severe pneumonia. Periodontal disease is often ignored by the public, and it is difficult for critical care physicians to link severe pneumonia with periodontal disease. Thus, this case represents an important warning to critical care clinicians.https://doi.org/10.1177/03000605231213760 |
| spellingShingle | Zhou Yuanjun Cai Yan Zhang Qingyan Xiong Feng -induced hematogenous disseminated severe pneumonia: a case report Journal of International Medical Research |
| title | -induced hematogenous disseminated severe pneumonia: a case report |
| title_full | -induced hematogenous disseminated severe pneumonia: a case report |
| title_fullStr | -induced hematogenous disseminated severe pneumonia: a case report |
| title_full_unstemmed | -induced hematogenous disseminated severe pneumonia: a case report |
| title_short | -induced hematogenous disseminated severe pneumonia: a case report |
| title_sort | induced hematogenous disseminated severe pneumonia a case report |
| url | https://doi.org/10.1177/03000605231213760 |
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