Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results

Summary: Metabolite genome-wide association studies (mGWAS) have advanced our understanding of the genetic control of metabolite levels. However, interpreting these associations remains challenging due to a lack of tools to annotate gene-metabolite pairs beyond the use of conservative statistical si...

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Hlavní autoři: Cantin Baron, Sarah Cherkaoui, Sandra Therrien-Laperriere, Yann Ilboudo, Raphaël Poujol, Pamela Mehanna, Melanie E. Garrett, Marilyn J. Telen, Allison E. Ashley-Koch, Pablo Bartolucci, John D. Rioux, Guillaume Lettre, Christine Des Rosiers, Matthieu Ruiz, Julie G. Hussin
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2023-12-01
Edice:iScience
Témata:
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2589004223025506