Functional analyses reveal extensive RRE plasticity in primary HIV-1 sequences selected under selective pressure.

Functional analyses reveal extensive RRE plasticity in primary HIV-1 sequences selected under selective pressure.

<h4>Background</h4>HIV-1 Rev response element (RRE) is a functional region of viral RNA lying immediately downstream to the junction of gp120 and gp41 in the env coding sequence. The RRE is essential for HIV replication and binds with the Rev protein to facilitate the export of viral mRN...

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Bibliographic Details
Main Authors: Francesc Cunyat, Nancy Beerens, Elisabet García, Bonaventura Clotet, Jørgen Kjems, Cecilia Cabrera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25170621/pdf/?tool=EBI

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