The association of maternal dietary quality and the antioxidant-proxidant balance of human milk
Abstract Background Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improvi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | International Breastfeeding Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13006-022-00498-1 |
| _version_ | 1811320825088835584 |
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| author | Samira Karbasi Afsane Bahrami Zahra Asadi Fatemeh Shahbeiki Mohsen Naseri Asghar Zarban Gordon A. Ferns |
| author_facet | Samira Karbasi Afsane Bahrami Zahra Asadi Fatemeh Shahbeiki Mohsen Naseri Asghar Zarban Gordon A. Ferns |
| author_sort | Samira Karbasi |
| collection | DOAJ |
| description | Abstract Background Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improving the health of both mothers and infants. Diet can enhance the oxidant-antioxidant balance of human milk. This study aimed to investigate the association between human milk oxidant-antioxidant balance with dietary patterns of lactating mothers identified by using principal component analysis. Method This cross-sectional study included 350 breastfeeding women between the ages of 20 to 35 years. The dietary intakes of the women in the study were estimated using a validated food frequency questionnaire, which included 65 food items. The oxidant-antioxidant balance of milk samples was assessed using the ferric reducing antioxidant power (FRAP), 2, 2′-diphenyl-1-picrylhydrazyl (DPPH), thiobarbituric acid reactive substances (TBARs), and Ellman’s assay. The milk concentration of total protein, calcium, and triglyceride was also measured using commercial kits. Result Two predominant dietary patterns were recognized that we defined as a healthy and unhealthy pattern. There were higher levels of DPPH and thiol in the milk from mothers in the third tertile (highest adherence) of a healthy dietary pattern compared to the first tertile (lowest adherence; p < 0.05). Milk calcium and thiol were significantly lower in the third tertile of mothers with an unhealthy dietary pattern versus the first tertile (P < 0.05). In multivariate multinomial logistic regression analyses adjusted for mother’s age, body mass index (BMI), energy intake, and infant’s sex, adherence to a healthy dietary pattern was associated with higher levels of milk DPPH (OR = 1.32, 95% confidence interval (CI): 1.01, 1.80) and milk thiol (OR = 1.21, 95% CI: 1.10, 1.50). On the other adherence to the unhealthy dietary pattern was correlated with low levels of milk thiol (OR = 1.29; 95%CI: 1.09, 1.59) and milk calcium (OR = 1.28; 95%CI: 1.11, 1.55). Conclusion Our findings demonstrated that adherence to a healthy dietary pattern, identified by higher consumption of green vegetables, other vegetables, and fruits is associated with a higher milk oxidant-antioxidant status in breastfeeding mothers. |
| first_indexed | 2024-04-13T13:07:31Z |
| format | Article |
| id | doaj.art-7aa68fcb77dd472298e39116d324fad7 |
| institution | Directory Open Access Journal |
| issn | 1746-4358 |
| language | English |
| last_indexed | 2024-04-13T13:07:31Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | International Breastfeeding Journal |
| spelling | doaj.art-7aa68fcb77dd472298e39116d324fad72022-12-22T02:45:44ZengBMCInternational Breastfeeding Journal1746-43582022-08-011711910.1186/s13006-022-00498-1The association of maternal dietary quality and the antioxidant-proxidant balance of human milkSamira Karbasi0Afsane Bahrami1Zahra Asadi2Fatemeh Shahbeiki3Mohsen Naseri4Asghar Zarban5Gordon A. Ferns6Department of Molecular Medicine, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical SciencesClinical Research Development Unit of Akbar Hospital, Mashhad University of Medical SciencesMetabolic Syndrome Research Center, Mashhad University of Medical SciencesLaboratory Technician in the Central Laboratory of Mashhad University of Medical SciencesCellular and Molecular Research Center, Birjand University of Medical SciencesCardiovascular Diseases Research Center, Birjand University of Medical SciencesBrighton & Sussex Medical School, Division of Medical EducationAbstract Background Human milk composition varies over time within an individual mother as well as between lactating mothers due to several factors including maternal health, diet, and nutritional status. Therefore, improving nutrition status during gestation and breastfeeding is crucial for improving the health of both mothers and infants. Diet can enhance the oxidant-antioxidant balance of human milk. This study aimed to investigate the association between human milk oxidant-antioxidant balance with dietary patterns of lactating mothers identified by using principal component analysis. Method This cross-sectional study included 350 breastfeeding women between the ages of 20 to 35 years. The dietary intakes of the women in the study were estimated using a validated food frequency questionnaire, which included 65 food items. The oxidant-antioxidant balance of milk samples was assessed using the ferric reducing antioxidant power (FRAP), 2, 2′-diphenyl-1-picrylhydrazyl (DPPH), thiobarbituric acid reactive substances (TBARs), and Ellman’s assay. The milk concentration of total protein, calcium, and triglyceride was also measured using commercial kits. Result Two predominant dietary patterns were recognized that we defined as a healthy and unhealthy pattern. There were higher levels of DPPH and thiol in the milk from mothers in the third tertile (highest adherence) of a healthy dietary pattern compared to the first tertile (lowest adherence; p < 0.05). Milk calcium and thiol were significantly lower in the third tertile of mothers with an unhealthy dietary pattern versus the first tertile (P < 0.05). In multivariate multinomial logistic regression analyses adjusted for mother’s age, body mass index (BMI), energy intake, and infant’s sex, adherence to a healthy dietary pattern was associated with higher levels of milk DPPH (OR = 1.32, 95% confidence interval (CI): 1.01, 1.80) and milk thiol (OR = 1.21, 95% CI: 1.10, 1.50). On the other adherence to the unhealthy dietary pattern was correlated with low levels of milk thiol (OR = 1.29; 95%CI: 1.09, 1.59) and milk calcium (OR = 1.28; 95%CI: 1.11, 1.55). Conclusion Our findings demonstrated that adherence to a healthy dietary pattern, identified by higher consumption of green vegetables, other vegetables, and fruits is associated with a higher milk oxidant-antioxidant status in breastfeeding mothers.https://doi.org/10.1186/s13006-022-00498-1Oxidant-antioxidant balanceDietary patternBreastfeeding mothersHuman milkInfant |
| spellingShingle | Samira Karbasi Afsane Bahrami Zahra Asadi Fatemeh Shahbeiki Mohsen Naseri Asghar Zarban Gordon A. Ferns The association of maternal dietary quality and the antioxidant-proxidant balance of human milk International Breastfeeding Journal Oxidant-antioxidant balance Dietary pattern Breastfeeding mothers Human milk Infant |
| title | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
| title_full | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
| title_fullStr | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
| title_full_unstemmed | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
| title_short | The association of maternal dietary quality and the antioxidant-proxidant balance of human milk |
| title_sort | association of maternal dietary quality and the antioxidant proxidant balance of human milk |
| topic | Oxidant-antioxidant balance Dietary pattern Breastfeeding mothers Human milk Infant |
| url | https://doi.org/10.1186/s13006-022-00498-1 |
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