Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021
Abstract Purpose Tuberculosis is a high-burden disease and a major health concern in China, especially among children and adolescents. The purpose of this study was to assess risk factors for diagnostic delay in students with pulmonary tuberculosis in Quzhou City in eastern China. Patients and metho...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-023-08516-1 |
| _version_ | 1797453744830414848 |
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| author | Yating Zhang Bingdong Zhan Xiaogang Hao Wei Wang Xing Zhang Chunfu Fang Min Wang |
| author_facet | Yating Zhang Bingdong Zhan Xiaogang Hao Wei Wang Xing Zhang Chunfu Fang Min Wang |
| author_sort | Yating Zhang |
| collection | DOAJ |
| description | Abstract Purpose Tuberculosis is a high-burden disease and a major health concern in China, especially among children and adolescents. The purpose of this study was to assess risk factors for diagnostic delay in students with pulmonary tuberculosis in Quzhou City in eastern China. Patients and methods Cases of PTB in students and relevant information in Quzhou from 2011 to 2021 were collected using the TB Management Information System. The outcome of interest was diagnostic delay (i.e. ≥ 28 days between symptom onset and treatment initiation). Risk factors for diagnostic delay were identified using multivariable logistic regression. Results A total of 629 students in Quzhou were diagnosed with PTB during the study period, of whom 55.5% were male. The median diagnostic delay was 18 days (Inter Quartile Range, [IQR]: 8–38) and 38.0% of the students had a diagnostic delay. Living in a rural area (adjusted odds ratio, [AOR]: 1.56, 95% confidence interval [CI:] 1.11–2.19), developing PTB symptoms in the first quarter of the year (AOR: 2.18, 95% CI: 1.40–3.40), and no sputum smear result (AOR: 8.73, 95% CI: 1.68–45.30) were significantly associated with a diagnostic delay. Discovery through health examinations (AOR: 0.33, 95% CI: 0.17–0.63) was associated with reduced risk of diagnostic delay. Conclusion Schools in rural areas should pay special attention to increasing student awareness of the symptoms of tuberculosis and provide health education on tuberculosis prevention and control to students and staff. |
| first_indexed | 2024-03-09T15:27:17Z |
| format | Article |
| id | doaj.art-7aacf197ede44c989e037293570a74e7 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-03-09T15:27:17Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-7aacf197ede44c989e037293570a74e72023-11-26T12:26:56ZengBMCBMC Infectious Diseases1471-23342023-08-012311910.1186/s12879-023-08516-1Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021Yating Zhang0Bingdong Zhan1Xiaogang Hao2Wei Wang3Xing Zhang4Chunfu Fang5Min Wang6School of Public Health, Zhejiang University of Traditional Chinese MedicineDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionDepartment of Tuberculosis Control and Prevention, Quzhou Center for Disease Control and PreventionAbstract Purpose Tuberculosis is a high-burden disease and a major health concern in China, especially among children and adolescents. The purpose of this study was to assess risk factors for diagnostic delay in students with pulmonary tuberculosis in Quzhou City in eastern China. Patients and methods Cases of PTB in students and relevant information in Quzhou from 2011 to 2021 were collected using the TB Management Information System. The outcome of interest was diagnostic delay (i.e. ≥ 28 days between symptom onset and treatment initiation). Risk factors for diagnostic delay were identified using multivariable logistic regression. Results A total of 629 students in Quzhou were diagnosed with PTB during the study period, of whom 55.5% were male. The median diagnostic delay was 18 days (Inter Quartile Range, [IQR]: 8–38) and 38.0% of the students had a diagnostic delay. Living in a rural area (adjusted odds ratio, [AOR]: 1.56, 95% confidence interval [CI:] 1.11–2.19), developing PTB symptoms in the first quarter of the year (AOR: 2.18, 95% CI: 1.40–3.40), and no sputum smear result (AOR: 8.73, 95% CI: 1.68–45.30) were significantly associated with a diagnostic delay. Discovery through health examinations (AOR: 0.33, 95% CI: 0.17–0.63) was associated with reduced risk of diagnostic delay. Conclusion Schools in rural areas should pay special attention to increasing student awareness of the symptoms of tuberculosis and provide health education on tuberculosis prevention and control to students and staff.https://doi.org/10.1186/s12879-023-08516-1Pulmonary tuberculosisDelayChildrenPatient delayHealth system delay |
| spellingShingle | Yating Zhang Bingdong Zhan Xiaogang Hao Wei Wang Xing Zhang Chunfu Fang Min Wang Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 BMC Infectious Diseases Pulmonary tuberculosis Delay Children Patient delay Health system delay |
| title | Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 |
| title_full | Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 |
| title_fullStr | Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 |
| title_full_unstemmed | Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 |
| title_short | Factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in Quzhou, China: results from the surveillance data 2011–2021 |
| title_sort | factors associated with diagnostic delay of pulmonary tuberculosis among children and adolescents in quzhou china results from the surveillance data 2011 2021 |
| topic | Pulmonary tuberculosis Delay Children Patient delay Health system delay |
| url | https://doi.org/10.1186/s12879-023-08516-1 |
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