To β or Not to β: How Important Is β-Catenin Dependent and Independent WNT Signaling in CLL?

To β or Not to β: How Important Is β-Catenin Dependent and Independent WNT Signaling in CLL?

WNT pathways play an important role in cancer development and progression, but WNT pathways can also inhibit growth in melanoma, prostate, and ovarian cancers. Chronic lymphocytic leukemia (CLL) is known for its overexpression of several WNT ligands and receptors. Canonical WNT signaling is β-cateni...

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Bibliographic Details
Main Authors: Karol D. Urbanek, Stephan Stilgenbauer, Daniel Mertens
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
WNT
ROR1
chronic lymphocytic leukemia
Online Access:https://www.mdpi.com/2072-6694/15/1/194

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