Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity

Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity

The understanding of the electrophysiological mechanisms that underlie mechanosensitivity of the sinoatrial node (SAN), the primary pacemaker of the heart, has been evolving over the past century. The heart is constantly exposed to a dynamic mechanical environment; as such, the SAN has numerous cano...

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Bibliographic Details
Main Authors: Daniel Turner, Chen Kang, Pietro Mesirca, Juan Hong, Matteo E. Mangoni, Alexey V. Glukhov, Rajan Sah
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
automaticity
ion channel
cardiac
stretch activated
calcium
heart rate
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.662410/full

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