Findings on the Relationship Between Intestinal Microbiome and Vasculitis
The microbiome has been implicated in small-, medium-, large-, and variable-vessel vasculitis. Dysbiosis can frequently be found in vasculitis patients with altered microbial diversity and abundance, compared with those with other diseases and healthy controls. Dominant bacteria discovered in differ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.908352/full |
| _version_ | 1818545600979795968 |
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| author | Boyuan Sun Boyuan Sun Xin He Xin He Wen Zhang |
| author_facet | Boyuan Sun Boyuan Sun Xin He Xin He Wen Zhang |
| author_sort | Boyuan Sun |
| collection | DOAJ |
| description | The microbiome has been implicated in small-, medium-, large-, and variable-vessel vasculitis. Dysbiosis can frequently be found in vasculitis patients with altered microbial diversity and abundance, compared with those with other diseases and healthy controls. Dominant bacteria discovered in different studies vary greatly, but in general, the intestinal microbiome in vasculitis patients tends to contain more pathogenic and less beneficial bacteria. Improvement or resolution of dysbiosis has been observed after treatment in a few longitudinal studies. In addition, some molecular changes in intestinal permeability and immune response have been found in animal models of vasculitis diseases. |
| first_indexed | 2024-12-12T07:42:14Z |
| format | Article |
| id | doaj.art-7aba18928315422083e10aeb3b7114f2 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-12T07:42:14Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-7aba18928315422083e10aeb3b7114f22022-12-22T00:32:44ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882022-06-011210.3389/fcimb.2022.908352908352Findings on the Relationship Between Intestinal Microbiome and VasculitisBoyuan Sun0Boyuan Sun1Xin He2Xin He3Wen Zhang4Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, ChinaM.D. Program, Peking Union Medical College, Beijing, ChinaDepartment of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, ChinaM.D. Program, Peking Union Medical College, Beijing, ChinaDepartment of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, State Key Laboratory of Complex Severe and Rare Diseases, Beijing, ChinaThe microbiome has been implicated in small-, medium-, large-, and variable-vessel vasculitis. Dysbiosis can frequently be found in vasculitis patients with altered microbial diversity and abundance, compared with those with other diseases and healthy controls. Dominant bacteria discovered in different studies vary greatly, but in general, the intestinal microbiome in vasculitis patients tends to contain more pathogenic and less beneficial bacteria. Improvement or resolution of dysbiosis has been observed after treatment in a few longitudinal studies. In addition, some molecular changes in intestinal permeability and immune response have been found in animal models of vasculitis diseases.https://www.frontiersin.org/articles/10.3389/fcimb.2022.908352/fullintestinal microbiomeantineutrophil cytoplasmic antibody-associated vasculitisimmunoglobulin A vasculitisBehcet’s diseaseKawasaki diseasevasculitis |
| spellingShingle | Boyuan Sun Boyuan Sun Xin He Xin He Wen Zhang Findings on the Relationship Between Intestinal Microbiome and Vasculitis Frontiers in Cellular and Infection Microbiology intestinal microbiome antineutrophil cytoplasmic antibody-associated vasculitis immunoglobulin A vasculitis Behcet’s disease Kawasaki disease vasculitis |
| title | Findings on the Relationship Between Intestinal Microbiome and Vasculitis |
| title_full | Findings on the Relationship Between Intestinal Microbiome and Vasculitis |
| title_fullStr | Findings on the Relationship Between Intestinal Microbiome and Vasculitis |
| title_full_unstemmed | Findings on the Relationship Between Intestinal Microbiome and Vasculitis |
| title_short | Findings on the Relationship Between Intestinal Microbiome and Vasculitis |
| title_sort | findings on the relationship between intestinal microbiome and vasculitis |
| topic | intestinal microbiome antineutrophil cytoplasmic antibody-associated vasculitis immunoglobulin A vasculitis Behcet’s disease Kawasaki disease vasculitis |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2022.908352/full |
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