Characterization of Monoclonal Antibodies against σA Protein and Cross-Reactive Epitope Identification and Application for Detection of Duck and Chicken Reovirus Infections

Characterization of Monoclonal Antibodies against σA Protein and Cross-Reactive Epitope Identification and Application for Detection of Duck and Chicken Reovirus Infections

Although σA is an important major core protein of duck reovirus (DRV), the B-cell epitopes of this protein remain unknown to reseacrhers. Six monoclonal antibodies (MAbs) (1A7, 3F4, 5D2, 4E2, 3C7, and 2B7) were developed by using prokaryotic-expressed recombinant His-σA protein. Fi...

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Bibliographic Details
Main Authors: Xueming Chen, Tongtong Li, Xiaodan Chen, Chenxi Li, Weiwei Lin, Hongyu Liu, Shuping Song, Xiaofei Bai, Yun Zhang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pathogens
Subjects:
duck reovirus
avian reovirus
turkey reovirus
monoclonal antibody
σA protein epitopes
cross-reactive epitopes
diagnosis
Online Access:https://www.mdpi.com/2076-0817/8/3/140

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