Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015
In August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death. We identified Reston ebolavirus (RESTV) infection in monkeys by using serologic and mol...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2018-07-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/24/7/17-1234_article |
| _version_ | 1818305697654243328 |
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| author | Catalino Demetria Ina Smith Titus Tan Daniel Villarico Edson Michael Simon Rex Centeno Mary Tachedjian Satoshi Taniguchi Masayuki Shimojima Noel Lee J. Miranda Mary Elizabeth Miranda Melissa Marie R. Rondina Rowena Capistrano Amado Tandoc Glenn Marsh Debbie Eagles Ramses Cruz Shuetsu Fukushi |
| author_facet | Catalino Demetria Ina Smith Titus Tan Daniel Villarico Edson Michael Simon Rex Centeno Mary Tachedjian Satoshi Taniguchi Masayuki Shimojima Noel Lee J. Miranda Mary Elizabeth Miranda Melissa Marie R. Rondina Rowena Capistrano Amado Tandoc Glenn Marsh Debbie Eagles Ramses Cruz Shuetsu Fukushi |
| author_sort | Catalino Demetria |
| collection | DOAJ |
| description | In August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death. We identified Reston ebolavirus (RESTV) infection in monkeys by using serologic and molecular assays. We isolated viruses in tissues from infected monkeys and determined viral genome sequences. RESTV found in the 2015 outbreak is genetically closer to 1 of the 4 RESTVs that caused the 2008 outbreak among swine. Eight macaques, including 2 also infected with RESTV, tested positive for measles. Concurrently, the measles virus was circulating throughout the Philippines, indicating that the infection of the macaques may be a reverse zoonosis. Improved biosecurity measures will minimize the public health risk, as well as limit the introduction of disease and vectors. |
| first_indexed | 2024-12-13T06:30:43Z |
| format | Article |
| id | doaj.art-7abca58e56574582972e6850edbdb225 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-13T06:30:43Z |
| publishDate | 2018-07-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-7abca58e56574582972e6850edbdb2252022-12-21T23:56:37ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592018-07-012471285129110.3201/eid2407.171234Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015Catalino DemetriaIna SmithTitus TanDaniel VillaricoEdson Michael SimonRex CentenoMary TachedjianSatoshi TaniguchiMasayuki ShimojimaNoel Lee J. MirandaMary Elizabeth MirandaMelissa Marie R. RondinaRowena CapistranoAmado TandocGlenn MarshDebbie EaglesRamses CruzShuetsu FukushiIn August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death. We identified Reston ebolavirus (RESTV) infection in monkeys by using serologic and molecular assays. We isolated viruses in tissues from infected monkeys and determined viral genome sequences. RESTV found in the 2015 outbreak is genetically closer to 1 of the 4 RESTVs that caused the 2008 outbreak among swine. Eight macaques, including 2 also infected with RESTV, tested positive for measles. Concurrently, the measles virus was circulating throughout the Philippines, indicating that the infection of the macaques may be a reverse zoonosis. Improved biosecurity measures will minimize the public health risk, as well as limit the introduction of disease and vectors.https://wwwnc.cdc.gov/eid/article/24/7/17-1234_articleReston Ebolavirusnon-human primatesmeasles viruscoinfectionmacaquesviruses |
| spellingShingle | Catalino Demetria Ina Smith Titus Tan Daniel Villarico Edson Michael Simon Rex Centeno Mary Tachedjian Satoshi Taniguchi Masayuki Shimojima Noel Lee J. Miranda Mary Elizabeth Miranda Melissa Marie R. Rondina Rowena Capistrano Amado Tandoc Glenn Marsh Debbie Eagles Ramses Cruz Shuetsu Fukushi Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 Emerging Infectious Diseases Reston Ebolavirus non-human primates measles virus coinfection macaques viruses |
| title | Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 |
| title_full | Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 |
| title_fullStr | Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 |
| title_full_unstemmed | Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 |
| title_short | Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 |
| title_sort | reemergence of reston ebolavirus in cynomolgus monkeys the philippines 2015 |
| topic | Reston Ebolavirus non-human primates measles virus coinfection macaques viruses |
| url | https://wwwnc.cdc.gov/eid/article/24/7/17-1234_article |
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