Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals
The formation of metal complexes with phytic acid is a complex process that depends strongly on the metal-to-ligand molar ratio, pH value and consequent protonation level of the phytate ligand as well as accompanying side reactions, in particular metal hydrolysis and precipitation of the formed coor...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-09-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fchem.2020.582746/full |
| _version_ | 1818235265195442176 |
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| author | Gregor Marolt Ema Gričar Boris Pihlar Mitja Kolar |
| author_facet | Gregor Marolt Ema Gričar Boris Pihlar Mitja Kolar |
| author_sort | Gregor Marolt |
| collection | DOAJ |
| description | The formation of metal complexes with phytic acid is a complex process that depends strongly on the metal-to-ligand molar ratio, pH value and consequent protonation level of the phytate ligand as well as accompanying side reactions, in particular metal hydrolysis and precipitation of the formed coordination compounds. In the present work, the potentiometric titration technique was used in combination with a detailed analysis of the equivalent point dependencies for selected biologically relevant monovalent and divalent cations from the groups of alkaline earths and transition metals, namely: Mg(II), Zn(II), Fe(II), Cu(I), and Cu(II) ions. The investigation of complex formation mechanism, the evaluation of the species formed, and the identification of other side reactions was based on the examination of three distinct equivalent points, which were detectable by alkalimetric titrations of phytic acid in the presence of selected metal ions. It has been demonstrated that alkaline earth metals interact with different binding site(s) than the transition metals, and experiments with both oxidation states of copper revealed similar complexing characteristics, which depend mainly on the ionic radius (and not on the ionic charge as initially expected). Quantitative data on phytate complexation, hydroxide formation and complex precipitation are presented herein for all metals studied, including Cu(I), which was investigated for the first time by means of alkalimetric titration. |
| first_indexed | 2024-12-12T11:51:13Z |
| format | Article |
| id | doaj.art-7ac57d0bb5524740a2db9654a2f324aa |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-12-12T11:51:13Z |
| publishDate | 2020-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-7ac57d0bb5524740a2db9654a2f324aa2022-12-22T00:25:18ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462020-09-01810.3389/fchem.2020.582746582746Complex Formation of Phytic Acid With Selected Monovalent and Divalent MetalsGregor MaroltEma GričarBoris PihlarMitja KolarThe formation of metal complexes with phytic acid is a complex process that depends strongly on the metal-to-ligand molar ratio, pH value and consequent protonation level of the phytate ligand as well as accompanying side reactions, in particular metal hydrolysis and precipitation of the formed coordination compounds. In the present work, the potentiometric titration technique was used in combination with a detailed analysis of the equivalent point dependencies for selected biologically relevant monovalent and divalent cations from the groups of alkaline earths and transition metals, namely: Mg(II), Zn(II), Fe(II), Cu(I), and Cu(II) ions. The investigation of complex formation mechanism, the evaluation of the species formed, and the identification of other side reactions was based on the examination of three distinct equivalent points, which were detectable by alkalimetric titrations of phytic acid in the presence of selected metal ions. It has been demonstrated that alkaline earth metals interact with different binding site(s) than the transition metals, and experiments with both oxidation states of copper revealed similar complexing characteristics, which depend mainly on the ionic radius (and not on the ionic charge as initially expected). Quantitative data on phytate complexation, hydroxide formation and complex precipitation are presented herein for all metals studied, including Cu(I), which was investigated for the first time by means of alkalimetric titration.https://www.frontiersin.org/article/10.3389/fchem.2020.582746/fullphytic acidinositol hexaphosphatemetal complexesmagnesiumzinciron |
| spellingShingle | Gregor Marolt Ema Gričar Boris Pihlar Mitja Kolar Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals Frontiers in Chemistry phytic acid inositol hexaphosphate metal complexes magnesium zinc iron |
| title | Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals |
| title_full | Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals |
| title_fullStr | Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals |
| title_full_unstemmed | Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals |
| title_short | Complex Formation of Phytic Acid With Selected Monovalent and Divalent Metals |
| title_sort | complex formation of phytic acid with selected monovalent and divalent metals |
| topic | phytic acid inositol hexaphosphate metal complexes magnesium zinc iron |
| url | https://www.frontiersin.org/article/10.3389/fchem.2020.582746/full |
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