The Infectious Dose Shapes Vibrio cholerae Within-Host Dynamics

The Infectious Dose Shapes Vibrio cholerae Within-Host Dynamics

ABSTRACT During infection, the rates of pathogen replication, death, and migration affect disease progression, dissemination, transmission, and resistance evolution. Here, we follow the population dynamics of Vibrio cholerae in a mouse model by labeling individual bacteria with one of >500 unique...

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Bibliographic Details
Main Authors: Aaron Nicholas Gillman, Anel Mahmutovic, Pia Abel zur Wiesch, Sören Abel
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSystems
Subjects:
founder population size
moment closure
particle swarm optimization
stochastic spatiotemporal population dynamics
dose response
Vibrio cholerae
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00659-21

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