Acceptance of oral chemotherapy in breast cancer patients - a survey study

<p>Abstract</p> <p>Background</p> <p>Oral (p.o.) chemotherapy treatments gained increasing importance in the palliative treatment of metastatic breast cancer (MBC). Aim of this survey was to evaluate the acceptance of p.o. treatment and patients' individual attitud...

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Main Authors: Sohn Christof, Domschke Christoph, Bruckner Thomas, Reinhardt Judith, Schneeweiss Andreas, Schott Sarah, Eichbaum Michael H
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/129
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author Sohn Christof
Domschke Christoph
Bruckner Thomas
Reinhardt Judith
Schneeweiss Andreas
Schott Sarah
Eichbaum Michael H
author_facet Sohn Christof
Domschke Christoph
Bruckner Thomas
Reinhardt Judith
Schneeweiss Andreas
Schott Sarah
Eichbaum Michael H
author_sort Sohn Christof
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Oral (p.o.) chemotherapy treatments gained increasing importance in the palliative treatment of metastatic breast cancer (MBC). Aim of this survey was to evaluate the acceptance of p.o. treatment and patients' individual attitudes towards it.</p> <p>Methods</p> <p>A specific 14 item-questionnaire was designed. Patients suffering from breast cancer receiving a newly launched p.o. or i.v. chemotherapy treatment were prospectively evaluated during 4 months of time. 224 questionnaires using descriptive statistics, chi-square test, Spearman correlation were evaluated.</p> <p>Results</p> <p>Patients' median age was 54 years, 164 received i.v., 60 p.o therapy. 89% with p.o. and 67% with i.v. regimens would choose p.o. over i.v. therapy, if equal efficacy is guaranteed. Significant differences were especially found in terms of personal benefit (55% i.v., 92% p.o.), reduced feeling of being ill due to p.o. treatment (26% i.v., 65% p.o.), better coping with disease due to p.o. therapy (36% i.v., 68% p.o.). Side effects were significantly less often reported under p.o. treatment (19% p.o. vs. 53% i.v.)</p> <p>Conclusion</p> <p>P.o. chemotherapy shows a high acceptance in MBC patients under palliative therapy. Compliance can be achieved in particular through a differentiated indication, patient education and competent support along a p.o. treatment.</p>
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spelling doaj.art-7ac72a9205aa4dd1a4143988343fc3a32022-12-21T20:46:57ZengBMCBMC Cancer1471-24072011-04-0111112910.1186/1471-2407-11-129Acceptance of oral chemotherapy in breast cancer patients - a survey studySohn ChristofDomschke ChristophBruckner ThomasReinhardt JudithSchneeweiss AndreasSchott SarahEichbaum Michael H<p>Abstract</p> <p>Background</p> <p>Oral (p.o.) chemotherapy treatments gained increasing importance in the palliative treatment of metastatic breast cancer (MBC). Aim of this survey was to evaluate the acceptance of p.o. treatment and patients' individual attitudes towards it.</p> <p>Methods</p> <p>A specific 14 item-questionnaire was designed. Patients suffering from breast cancer receiving a newly launched p.o. or i.v. chemotherapy treatment were prospectively evaluated during 4 months of time. 224 questionnaires using descriptive statistics, chi-square test, Spearman correlation were evaluated.</p> <p>Results</p> <p>Patients' median age was 54 years, 164 received i.v., 60 p.o therapy. 89% with p.o. and 67% with i.v. regimens would choose p.o. over i.v. therapy, if equal efficacy is guaranteed. Significant differences were especially found in terms of personal benefit (55% i.v., 92% p.o.), reduced feeling of being ill due to p.o. treatment (26% i.v., 65% p.o.), better coping with disease due to p.o. therapy (36% i.v., 68% p.o.). Side effects were significantly less often reported under p.o. treatment (19% p.o. vs. 53% i.v.)</p> <p>Conclusion</p> <p>P.o. chemotherapy shows a high acceptance in MBC patients under palliative therapy. Compliance can be achieved in particular through a differentiated indication, patient education and competent support along a p.o. treatment.</p>http://www.biomedcentral.com/1471-2407/11/129
spellingShingle Sohn Christof
Domschke Christoph
Bruckner Thomas
Reinhardt Judith
Schneeweiss Andreas
Schott Sarah
Eichbaum Michael H
Acceptance of oral chemotherapy in breast cancer patients - a survey study
BMC Cancer
title Acceptance of oral chemotherapy in breast cancer patients - a survey study
title_full Acceptance of oral chemotherapy in breast cancer patients - a survey study
title_fullStr Acceptance of oral chemotherapy in breast cancer patients - a survey study
title_full_unstemmed Acceptance of oral chemotherapy in breast cancer patients - a survey study
title_short Acceptance of oral chemotherapy in breast cancer patients - a survey study
title_sort acceptance of oral chemotherapy in breast cancer patients a survey study
url http://www.biomedcentral.com/1471-2407/11/129
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