Genetic Code Optimization for Cotranslational Protein Folding: Codon Directional Asymmetry Correlates with Antiparallel Betasheets, tRNA Synthetase Classes
A new codon property, codon directional asymmetry in nucleotide content (CDA), reveals a biologically meaningful genetic code dimension: palindromic codons (first and last nucleotides identical, codon structure XZX) are symmetric (CDA = 0), codons with structures ZXX/XXZ are 5′/3′ asymmetric (CDA = ...
Main Authors: | Hervé Seligmann, Ganesh Warthi |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-01-01
|
Series: | Computational and Structural Biotechnology Journal |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037017300636 |
Similar Items
-
Cotranslational Folding of Proteins on the Ribosome
by: Marija Liutkute, et al.
Published: (2020-01-01) -
Cotranslational protein folding--fact or fiction?
by: Deane, C, et al.
Published: (2007) -
Cotranslational protein folding - fact or fiction?
by: Deane, C, et al.
Published: (2007) -
Pyrrolysyl-tRNA Synthetase, an Aminoacyl-tRNA Synthetase for Genetic Code Expansion
by: Ana Crnković, et al.
Published: (2016-06-01) -
Transcripts with systematic nucleotide deletion of 1-12 nucleotide in human mitochondrion suggest potential non-canonical transcription.
by: Ganesh Warthi, et al.
Published: (2019-01-01)