A standardized pomegranate fruit extract ameliorates thioacetamide-induced liver fibrosis in rats via AGE-RAGE-ROS signaling

A standardized pomegranate fruit extract ameliorates thioacetamide-induced liver fibrosis in rats via AGE-RAGE-ROS signaling

This work aimed to investigate a possible mechanism that may mediate the hepatoprotective effects of pomegranate fruit extract (PFE) against thioacetamide (THIO)-induced liver fibrosis in rats. Male Sprague Dawley rats were randomly allocated into four groups (n = 8 each): control; PFE (150 mg/kg/da...

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Bibliographic Details
Main Authors: Hadeer M. Abouelezz, George S.G. Shehatou, Abdelhadi M. Shebl, Hatem A. Salem
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Thioacetamide
Liver fibrosis
Pomegranate fruit extract
Oxidative stress
RAGE
TGF-β1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023014639

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