Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties

The influence of different surface properties holding to a modification of the substrate towards hydrophobic or superhydrophobic behavior was reviewed in this paper. Cell adhesion, their communication, and proliferation can be strongly manipulated, acting on interfacial relationship involving stiffn...

Full description

Bibliographic Details
Main Authors: Michele Ferrari, Francesca Cirisano, and M. Carmen Morán
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Colloids and Interfaces
Subjects:
Online Access:https://www.mdpi.com/2504-5377/3/2/48
_version_ 1819094598198231040
author Michele Ferrari
Francesca Cirisano
and M. Carmen Morán
author_facet Michele Ferrari
Francesca Cirisano
and M. Carmen Morán
author_sort Michele Ferrari
collection DOAJ
description The influence of different surface properties holding to a modification of the substrate towards hydrophobic or superhydrophobic behavior was reviewed in this paper. Cell adhesion, their communication, and proliferation can be strongly manipulated, acting on interfacial relationship involving stiffness, surface charge, surface chemistry, roughness, or wettability. All these features can play mutual roles in determining the final properties of biomedical applications ranging from fabrics to cell biology devices. The focus of this work is the mammalian cell viability in contact with moderate to highly water repellent coatings or materials and also in combination with hydrophilic areas for more specific application. Few case studies illustrate a range of examples in which these surface properties and design can be fruitfully matched to the specific aim.
first_indexed 2024-12-21T23:29:57Z
format Article
id doaj.art-7ad76f3b425945baabd43f7d7890d05d
institution Directory Open Access Journal
issn 2504-5377
language English
last_indexed 2024-12-21T23:29:57Z
publishDate 2019-05-01
publisher MDPI AG
record_format Article
series Colloids and Interfaces
spelling doaj.art-7ad76f3b425945baabd43f7d7890d05d2022-12-21T18:46:32ZengMDPI AGColloids and Interfaces2504-53772019-05-01324810.3390/colloids3020048colloids3020048Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface PropertiesMichele Ferrari0Francesca Cirisano1and M. Carmen Morán2CNR-ICMATE Istituto di Chimica della Materia Condensata e di Tecnologie per l’Energia, via De Marini, 6, 16149 Genova, ItalyCNR-ICMATE Istituto di Chimica della Materia Condensata e di Tecnologie per l’Energia, via De Marini, 6, 16149 Genova, ItalyInstitut de Nanociència i Nanotecnologia – IN2UB, Universitat de Barcelona, Avda. Diagonal, 645, 08028 Barcelona, SpainThe influence of different surface properties holding to a modification of the substrate towards hydrophobic or superhydrophobic behavior was reviewed in this paper. Cell adhesion, their communication, and proliferation can be strongly manipulated, acting on interfacial relationship involving stiffness, surface charge, surface chemistry, roughness, or wettability. All these features can play mutual roles in determining the final properties of biomedical applications ranging from fabrics to cell biology devices. The focus of this work is the mammalian cell viability in contact with moderate to highly water repellent coatings or materials and also in combination with hydrophilic areas for more specific application. Few case studies illustrate a range of examples in which these surface properties and design can be fruitfully matched to the specific aim.https://www.mdpi.com/2504-5377/3/2/48biological applicationscell adhesionhydrophobicitysuperhydrophobicitymammalian cellsprotein adsorptionsurfaces propertieswettability
spellingShingle Michele Ferrari
Francesca Cirisano
and M. Carmen Morán
Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
Colloids and Interfaces
biological applications
cell adhesion
hydrophobicity
superhydrophobicity
mammalian cells
protein adsorption
surfaces properties
wettability
title Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
title_full Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
title_fullStr Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
title_full_unstemmed Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
title_short Mammalian Cell Behavior on Hydrophobic Substrates: Influence of Surface Properties
title_sort mammalian cell behavior on hydrophobic substrates influence of surface properties
topic biological applications
cell adhesion
hydrophobicity
superhydrophobicity
mammalian cells
protein adsorption
surfaces properties
wettability
url https://www.mdpi.com/2504-5377/3/2/48
work_keys_str_mv AT micheleferrari mammaliancellbehavioronhydrophobicsubstratesinfluenceofsurfaceproperties
AT francescacirisano mammaliancellbehavioronhydrophobicsubstratesinfluenceofsurfaceproperties
AT andmcarmenmoran mammaliancellbehavioronhydrophobicsubstratesinfluenceofsurfaceproperties