Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults
Abstract Background/aim Evidence from recent studies suggested that the quality of dietary macronutrients can play a possible role in predicting the risk of metabolic disorders. In the current study, we aimed to assess the association of carbohydrate quality index (CQI) and protein score with the ri...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-024-03779-1 |
| _version_ | 1797275992478187520 |
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| author | Hossein Farhadnejad Ebrahim Mokhtari Farshad Teymoori Mitra Kazemi Jahromi Niloufar Saber Hamid Ahmadirad Mostafa Norouzzadeh Parvin Mirmiran Fereidoun Azizi |
| author_facet | Hossein Farhadnejad Ebrahim Mokhtari Farshad Teymoori Mitra Kazemi Jahromi Niloufar Saber Hamid Ahmadirad Mostafa Norouzzadeh Parvin Mirmiran Fereidoun Azizi |
| author_sort | Hossein Farhadnejad |
| collection | DOAJ |
| description | Abstract Background/aim Evidence from recent studies suggested that the quality of dietary macronutrients can play a possible role in predicting the risk of metabolic disorders. In the current study, we aimed to assess the association of carbohydrate quality index (CQI) and protein score with the risk of metabolic syndrome (MetS) in Iranian adults. Methods This prospective study was conducted within the framework of the Tehran Lipid and Glucose Study on 1738 individuals aged between 40 and 70 years old, who were followed up for a mean of 6.1 years. A food frequency questionnaire was used to determine CQI and protein scores. The multivariable adjusted Cox regression model was used to calculate the hazard ratio (HR) of MetS across quartiles of protein score and CQI, and its components. Results The mean ± standard deviation (SD) age and body mass index of the study population (42.5% men) were 49.3 ± 7.5 years and 27.0 ± 4.0 kg/m2, respectively. Mean ± SD scores of CQI and protein for all participants were 12.6 ± 2.4 and 10.3 ± 3.5, respectively. During the study follow-up, 834(48.0%) new cases of MetS were ascertained. In the multivariable-adjusted model, the risk of MetS was decreased across quartiles of CQI (HR = 0.83;95%CI:0.69–1.00, Ptrend=0.025) and protein score (HR = 0.75; 95% CI:0.60–0.94, Ptrend=0.041). Also, Of CQI components, the whole grain/total grains ratio showed a significant inverse association with the risk of MetS (HR = 0.75;95%CI:0.60–0.94, Ptrend=0.012). Conclusion Our findings revealed that a dietary pattern with higher CQI and protein score may be related to a reduced risk of MetS in adults. |
| first_indexed | 2024-03-07T15:21:00Z |
| format | Article |
| id | doaj.art-7ada478dff6d453fbf7454119e1c1726 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-03-07T15:21:00Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-7ada478dff6d453fbf7454119e1c17262024-03-05T17:37:48ZengBMCBMC Cardiovascular Disorders1471-22612024-02-0124111210.1186/s12872-024-03779-1Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adultsHossein Farhadnejad0Ebrahim Mokhtari1Farshad Teymoori2Mitra Kazemi Jahromi3Niloufar Saber4Hamid Ahmadirad5Mostafa Norouzzadeh6Parvin Mirmiran7Fereidoun Azizi8Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesEndocrinology and Metabolism Research Center, Hormozgan University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesAbstract Background/aim Evidence from recent studies suggested that the quality of dietary macronutrients can play a possible role in predicting the risk of metabolic disorders. In the current study, we aimed to assess the association of carbohydrate quality index (CQI) and protein score with the risk of metabolic syndrome (MetS) in Iranian adults. Methods This prospective study was conducted within the framework of the Tehran Lipid and Glucose Study on 1738 individuals aged between 40 and 70 years old, who were followed up for a mean of 6.1 years. A food frequency questionnaire was used to determine CQI and protein scores. The multivariable adjusted Cox regression model was used to calculate the hazard ratio (HR) of MetS across quartiles of protein score and CQI, and its components. Results The mean ± standard deviation (SD) age and body mass index of the study population (42.5% men) were 49.3 ± 7.5 years and 27.0 ± 4.0 kg/m2, respectively. Mean ± SD scores of CQI and protein for all participants were 12.6 ± 2.4 and 10.3 ± 3.5, respectively. During the study follow-up, 834(48.0%) new cases of MetS were ascertained. In the multivariable-adjusted model, the risk of MetS was decreased across quartiles of CQI (HR = 0.83;95%CI:0.69–1.00, Ptrend=0.025) and protein score (HR = 0.75; 95% CI:0.60–0.94, Ptrend=0.041). Also, Of CQI components, the whole grain/total grains ratio showed a significant inverse association with the risk of MetS (HR = 0.75;95%CI:0.60–0.94, Ptrend=0.012). Conclusion Our findings revealed that a dietary pattern with higher CQI and protein score may be related to a reduced risk of MetS in adults.https://doi.org/10.1186/s12872-024-03779-1MacronutrientsCarbohydrate qualityProtein scoreMetabolic syndromeCardiovascular risk factorsAdults |
| spellingShingle | Hossein Farhadnejad Ebrahim Mokhtari Farshad Teymoori Mitra Kazemi Jahromi Niloufar Saber Hamid Ahmadirad Mostafa Norouzzadeh Parvin Mirmiran Fereidoun Azizi Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults BMC Cardiovascular Disorders Macronutrients Carbohydrate quality Protein score Metabolic syndrome Cardiovascular risk factors Adults |
| title | Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults |
| title_full | Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults |
| title_fullStr | Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults |
| title_full_unstemmed | Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults |
| title_short | Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults |
| title_sort | macronutrients quality indices and risk of metabolic syndrome and its components in iranian adults |
| topic | Macronutrients Carbohydrate quality Protein score Metabolic syndrome Cardiovascular risk factors Adults |
| url | https://doi.org/10.1186/s12872-024-03779-1 |
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