FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production

FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production

Foot-and-mouth disease virus (FMDV) infection causes inflammatory clinical symptoms, such as high fever and vesicular lesions, even death of animals. Interleukin-1β (IL-1β) is an inflammatory cytokine that plays an essential role in inflammatory responses against viral infection. The viruses have de...

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Bibliographic Details
Main Authors: Sk Mohiuddin Choudhury, Xusheng Ma, Yuanyuan Li, Xiaofeng Nian, Zhikuan Luo, Yonghua Ma, Zixiang Zhu, Fan Yang, Weijun Cao, Haixue Zheng
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
foot-and-mouth disease virus
inflammation
NLRP3
leader protein
NF-κB
ion channel
Online Access:https://www.mdpi.com/1999-4915/14/1/22

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