Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor
Background and Purpose Stereotactic thalamotomy has been an effective surgical procedure in the treatment of medically refractory essential tremor (ET), however, little is known about the bilateral effects of unilateral ventralis intermedius (Vim) thalamotomy and Vim deep brain stimulation (DBS). We...
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| Format: | Article |
| Language: | English |
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Korean Movement Disorder Society
2011-10-01
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| Series: | Journal of Movement Disorders |
| Subjects: | |
| Online Access: | http://e-jmd.org/upload/jmd-4-2-64-3.pdf |
| _version_ | 1797715987574816768 |
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| author | Mi J. Kim Sang R. Jeon Sung R. Kim Myoung C. Lee Sun J. Chung |
| author_facet | Mi J. Kim Sang R. Jeon Sung R. Kim Myoung C. Lee Sun J. Chung |
| author_sort | Mi J. Kim |
| collection | DOAJ |
| description | Background and Purpose Stereotactic thalamotomy has been an effective surgical procedure in the treatment of medically refractory essential tremor (ET), however, little is known about the bilateral effects of unilateral ventralis intermedius (Vim) thalamotomy and Vim deep brain stimulation (DBS). We studied the lateralized effects of unilateral Vim thalamotomy and Vim DBS in ET patients. Methods Vim thalamotomy was performed in 6 patients and Vim DBS in 6. Patients were evaluated preoperatively and at 3 and 6 months postoperatively using the Clinical Rating Scale for Tremor (CRST). Results The contralateral Part A (tremor localization/severity rating) and Part B (specific motor tasks/function rating) subscores, and axial subscores of CRST significantly improved after unilateral Vim thalamotomy or Vim DBS. On the side ipsilateral to surgery, ET patients demonstrated no significant improvements in the Part A and Part B subscores of CRST. The Part C (functional disabilities resulting from tremor) subscores and total scores of CRST were significantly improved after surgery. Conclusions Vim thalamotomy and DBS may be equally effective for the management of contralateral and axial tremor in ET patients, but both interventions may not improve tremor on the side ipsilateral to surgery. |
| first_indexed | 2024-03-12T08:15:52Z |
| format | Article |
| id | doaj.art-7ae0c5eedfc3415a88cbaedb74eff149 |
| institution | Directory Open Access Journal |
| issn | 2005-940X 2093-4939 |
| language | English |
| last_indexed | 2024-03-12T08:15:52Z |
| publishDate | 2011-10-01 |
| publisher | Korean Movement Disorder Society |
| record_format | Article |
| series | Journal of Movement Disorders |
| spelling | doaj.art-7ae0c5eedfc3415a88cbaedb74eff1492023-09-02T18:56:14ZengKorean Movement Disorder SocietyJournal of Movement Disorders2005-940X2093-49392011-10-0142646710.14802/jmd.1101325Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential TremorMi J. KimSang R. JeonSung R. KimMyoung C. LeeSun J. ChungBackground and Purpose Stereotactic thalamotomy has been an effective surgical procedure in the treatment of medically refractory essential tremor (ET), however, little is known about the bilateral effects of unilateral ventralis intermedius (Vim) thalamotomy and Vim deep brain stimulation (DBS). We studied the lateralized effects of unilateral Vim thalamotomy and Vim DBS in ET patients. Methods Vim thalamotomy was performed in 6 patients and Vim DBS in 6. Patients were evaluated preoperatively and at 3 and 6 months postoperatively using the Clinical Rating Scale for Tremor (CRST). Results The contralateral Part A (tremor localization/severity rating) and Part B (specific motor tasks/function rating) subscores, and axial subscores of CRST significantly improved after unilateral Vim thalamotomy or Vim DBS. On the side ipsilateral to surgery, ET patients demonstrated no significant improvements in the Part A and Part B subscores of CRST. The Part C (functional disabilities resulting from tremor) subscores and total scores of CRST were significantly improved after surgery. Conclusions Vim thalamotomy and DBS may be equally effective for the management of contralateral and axial tremor in ET patients, but both interventions may not improve tremor on the side ipsilateral to surgery.http://e-jmd.org/upload/jmd-4-2-64-3.pdfEssential tremorThalamotomyDeep brain stimulation |
| spellingShingle | Mi J. Kim Sang R. Jeon Sung R. Kim Myoung C. Lee Sun J. Chung Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor Journal of Movement Disorders Essential tremor Thalamotomy Deep brain stimulation |
| title | Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor |
| title_full | Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor |
| title_fullStr | Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor |
| title_full_unstemmed | Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor |
| title_short | Lateralized Effects of Unilateral Thalamotomy and Thalamic Stimulation in Patients with Essential Tremor |
| title_sort | lateralized effects of unilateral thalamotomy and thalamic stimulation in patients with essential tremor |
| topic | Essential tremor Thalamotomy Deep brain stimulation |
| url | http://e-jmd.org/upload/jmd-4-2-64-3.pdf |
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