Impact of timing of delivery for type 2 diabetes on perinatal outcomes
Aims: To compare obstetric and neonatal outcomes in patients with type 2 diabetes mellitus (T2DM) who had scheduled delivery at full term (≥ 39 0/7 weeks) compared to early term (37 0/7 – 38 6/7 weeks) for T2DM indications. Methods: This was a retrospective cohort study that included all singletons...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Diabetes Epidemiology and Management |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666970624000015 |
| _version_ | 1827378194082168832 |
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| author | Katarina Q. Watson Akshaya Kannan Nasim C. Sobhani |
| author_facet | Katarina Q. Watson Akshaya Kannan Nasim C. Sobhani |
| author_sort | Katarina Q. Watson |
| collection | DOAJ |
| description | Aims: To compare obstetric and neonatal outcomes in patients with type 2 diabetes mellitus (T2DM) who had scheduled delivery at full term (≥ 39 0/7 weeks) compared to early term (37 0/7 – 38 6/7 weeks) for T2DM indications. Methods: This was a retrospective cohort study that included all singletons with T2DM with a scheduled delivery at a single tertiary care center between January 2008 and March 2022. Outcomes were compared using Fisher's exact test. Results: 107 singleton pregnancies were included. There was no significant difference in primary cesarean delivery between the two groups. The early term group had significantly higher rates of NICU admission compared to the term group (52% vs 32%, p = 0.05, OR 2.3, 95% CI 1.0–5.0), a finding that remained statistically significant on adjusted analysis (adjusted OR 2.81, 95% CI 1.04–7.58). Conclusions: In singleton pregnancies undergoing scheduled delivery for T2DM-specific indications, early term deliveries were associated with significantly increased odds of NICU admission when compared to term deliveries, even after adjusting for surrogate markers of glycemic control. These findings suggest that early term delivery contributes to risk of NICU admission, rather than the indication for delivery itself. These findings should be replicated in a larger cohort. |
| first_indexed | 2024-03-08T12:51:31Z |
| format | Article |
| id | doaj.art-7ae9d3c9ac0846c88484fb8f84f13e10 |
| institution | Directory Open Access Journal |
| issn | 2666-9706 |
| language | English |
| last_indexed | 2024-03-08T12:51:31Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Diabetes Epidemiology and Management |
| spelling | doaj.art-7ae9d3c9ac0846c88484fb8f84f13e102024-01-20T04:46:48ZengElsevierDiabetes Epidemiology and Management2666-97062024-04-0114100196Impact of timing of delivery for type 2 diabetes on perinatal outcomesKatarina Q. Watson0Akshaya Kannan1Nasim C. Sobhani2University of California, San Francisco School of Medicine, 533 Parnassus Avenue, San Francisco, CA 94143, United States; Corresponding author.Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, United StatesDepartment of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Francisco, United StatesAims: To compare obstetric and neonatal outcomes in patients with type 2 diabetes mellitus (T2DM) who had scheduled delivery at full term (≥ 39 0/7 weeks) compared to early term (37 0/7 – 38 6/7 weeks) for T2DM indications. Methods: This was a retrospective cohort study that included all singletons with T2DM with a scheduled delivery at a single tertiary care center between January 2008 and March 2022. Outcomes were compared using Fisher's exact test. Results: 107 singleton pregnancies were included. There was no significant difference in primary cesarean delivery between the two groups. The early term group had significantly higher rates of NICU admission compared to the term group (52% vs 32%, p = 0.05, OR 2.3, 95% CI 1.0–5.0), a finding that remained statistically significant on adjusted analysis (adjusted OR 2.81, 95% CI 1.04–7.58). Conclusions: In singleton pregnancies undergoing scheduled delivery for T2DM-specific indications, early term deliveries were associated with significantly increased odds of NICU admission when compared to term deliveries, even after adjusting for surrogate markers of glycemic control. These findings suggest that early term delivery contributes to risk of NICU admission, rather than the indication for delivery itself. These findings should be replicated in a larger cohort.http://www.sciencedirect.com/science/article/pii/S2666970624000015Diabetes in pregnancyT2DMNeonatal outcomesNICUEarly termDelivery timing |
| spellingShingle | Katarina Q. Watson Akshaya Kannan Nasim C. Sobhani Impact of timing of delivery for type 2 diabetes on perinatal outcomes Diabetes Epidemiology and Management Diabetes in pregnancy T2DM Neonatal outcomes NICU Early term Delivery timing |
| title | Impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| title_full | Impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| title_fullStr | Impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| title_full_unstemmed | Impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| title_short | Impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| title_sort | impact of timing of delivery for type 2 diabetes on perinatal outcomes |
| topic | Diabetes in pregnancy T2DM Neonatal outcomes NICU Early term Delivery timing |
| url | http://www.sciencedirect.com/science/article/pii/S2666970624000015 |
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