Pulmonary vasodilation by sildenafil in acute intermediate-high risk pulmonary embolism: a randomized explorative trial

Pulmonary vasodilation by sildenafil in acute intermediate-high risk pulmonary embolism: a randomized explorative trial

Abstract Background To investigate if acute pulmonary vasodilation by sildenafil improves right ventricular function in patients with acute intermediate-high risk pulmonary embolism (PE). Methods Single center, explorative trial. Patients with PE were randomized to a single oral dose of sildenafil 5...

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Bibliographic Details
Main Authors: Asger Andersen, Farhad Waziri, Jacob Gammelgaard Schultz, Sarah Holmboe, Søren Warberg Becker, Tage Jensen, Hanne Maare Søndergaard, Karen Kaae Dodt, Ole May, Ulrik Markus Mortensen, Won Yong Kim, Søren Mellemkjær, Jens Erik Nielsen-Kudsk
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Pulmonary Medicine
Subjects:
Pulmonary embolism
Sildenafil
PDE5 inhibition
Pulmonary vasodilation
Online Access:https://doi.org/10.1186/s12890-021-01440-7

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