Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling

Hematology: Preserving a stable home for stem cells Steady production of immune and blood cells depends on a signaling protein that helps maintain stable stem cell populations within the bone marrow. Hematopoietic stem cells (HSCs), which give rise to blood cells, reside within a supportive “niche”...

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Bibliographic Details
Main Authors: Seon-Yeong Jeong, Jungmook Lyu, Jin-A Kim, Il-Hoan Oh
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-020-0477-y