Insights into Online microRNA Bioinformatics Tools

MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognit...

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Principais autores: Diana Luna Buitrago, Ruth C. Lovering, Andrea Caporali
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2023-03-01
coleção:Non-Coding RNA
Assuntos:
Acesso em linha:https://www.mdpi.com/2311-553X/9/2/18
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author Diana Luna Buitrago
Ruth C. Lovering
Andrea Caporali
author_facet Diana Luna Buitrago
Ruth C. Lovering
Andrea Caporali
author_sort Diana Luna Buitrago
collection DOAJ
description MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs.
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spelling doaj.art-7aec0b55538c480584d4fb3c9e8c829f2023-11-17T20:44:28ZengMDPI AGNon-Coding RNA2311-553X2023-03-01921810.3390/ncrna9020018Insights into Online microRNA Bioinformatics ToolsDiana Luna Buitrago0Ruth C. Lovering1Andrea Caporali2BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh EH164TJ, UKFunctional Gene Annotation, Institute of Cardiovascular Science, University College London, London WC1E 6BT, UKBHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh EH164TJ, UKMicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs.https://www.mdpi.com/2311-553X/9/2/18miRNAsbioinformaticsdatabaseweb-based tools
spellingShingle Diana Luna Buitrago
Ruth C. Lovering
Andrea Caporali
Insights into Online microRNA Bioinformatics Tools
Non-Coding RNA
miRNAs
bioinformatics
database
web-based tools
title Insights into Online microRNA Bioinformatics Tools
title_full Insights into Online microRNA Bioinformatics Tools
title_fullStr Insights into Online microRNA Bioinformatics Tools
title_full_unstemmed Insights into Online microRNA Bioinformatics Tools
title_short Insights into Online microRNA Bioinformatics Tools
title_sort insights into online microrna bioinformatics tools
topic miRNAs
bioinformatics
database
web-based tools
url https://www.mdpi.com/2311-553X/9/2/18
work_keys_str_mv AT dianalunabuitrago insightsintoonlinemicrornabioinformaticstools
AT ruthclovering insightsintoonlinemicrornabioinformaticstools
AT andreacaporali insightsintoonlinemicrornabioinformaticstools