Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

One obstacle to the successful delivery of nanodrugs into solid tumors is the heterogeneity of an enhanced permeability and retention (EPR) effect as a result of occluded or embolized tumor blood vessels. Therefore, the augmentation of the EPR effect is critical for satisfactory anticancer nanomedic...

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Bibliographic Details
Main Authors: Jun Fang, Rayhanul Islam, Waliul Islam, Hongzhuan Yin, Vladimir Subr, Tomas Etrych, Karel Ulbrich, Hiroshi Maeda
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
EPR effect
nanomedicine
carbon monoxide
PDT
nanoprobe
Online Access:https://www.mdpi.com/1999-4923/11/7/343

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