Potential role of lysine succinylation in the response of moths to artificial light at night stress
Artificial light at night (ALAN) is a widespread environmental pollutant and stressor. Many nocturnal insects have been shown to experience ALAN stress. However, few studies have been conducted to uncover the mechanism by which nocturnal insects respond to ALAN stress. Previous studies suggest that...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-09-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651321004450 |
| _version_ | 1819066680205115392 |
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| author | Zhijuan Huang Li He Wen Sang Lijun Wang Qiuying Huang Chaoliang Lei |
| author_facet | Zhijuan Huang Li He Wen Sang Lijun Wang Qiuying Huang Chaoliang Lei |
| author_sort | Zhijuan Huang |
| collection | DOAJ |
| description | Artificial light at night (ALAN) is a widespread environmental pollutant and stressor. Many nocturnal insects have been shown to experience ALAN stress. However, few studies have been conducted to uncover the mechanism by which nocturnal insects respond to ALAN stress. Previous studies suggest that lysine succinylation (Ksuc) is a potential mechanism that coordinates energy metabolism and antioxidant activity under stressful conditions. Mythimna separata (Walker) (M. separata) is a nocturnal insect that has been stressed by ALAN. In this study, we quantified the relative proteomic Ksuc levels in ALAN-stressed M. separata. Of the 466 identified Ksuc-modified proteins, 103 were hypersuccinylated/desuccinylated in ALAN-stressed moths. The hypersuccinylated/desuccinylated proteins were shown to be involved in various biological processes. In particular, they were enriched in metabolic processes, reactive oxygen species (ROS) homeostasis and the neuromuscular system. Furthermore, we demonstrated that Ksuc might affect moth locomotion by intervening with and coordinating these systems under ALAN stress. These findings suggest that Ksuc plays a vital role in the moth response to ALAN stress and moth locomotion behavior and provide a new perspective on the impact of ALAN on nocturnal insect populations and species communities. |
| first_indexed | 2024-12-21T16:06:12Z |
| format | Article |
| id | doaj.art-7aed1a58ef2149978288faf8919b7d0d |
| institution | Directory Open Access Journal |
| issn | 0147-6513 |
| language | English |
| last_indexed | 2024-12-21T16:06:12Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj.art-7aed1a58ef2149978288faf8919b7d0d2022-12-21T18:57:53ZengElsevierEcotoxicology and Environmental Safety0147-65132021-09-01220112334Potential role of lysine succinylation in the response of moths to artificial light at night stressZhijuan Huang0Li He1Wen Sang2Lijun Wang3Qiuying Huang4Chaoliang Lei5Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaDepartment of Entomology, South China Agricultural University, Guangzhou 510640, ChinaCollege of Life Sciences, Yantai University, Yantai 264005, ChinaHubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Corresponding authors.Hubei Insect Resources Utilization and Sustainable Pest Management Key Laboratory, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Corresponding authors.Artificial light at night (ALAN) is a widespread environmental pollutant and stressor. Many nocturnal insects have been shown to experience ALAN stress. However, few studies have been conducted to uncover the mechanism by which nocturnal insects respond to ALAN stress. Previous studies suggest that lysine succinylation (Ksuc) is a potential mechanism that coordinates energy metabolism and antioxidant activity under stressful conditions. Mythimna separata (Walker) (M. separata) is a nocturnal insect that has been stressed by ALAN. In this study, we quantified the relative proteomic Ksuc levels in ALAN-stressed M. separata. Of the 466 identified Ksuc-modified proteins, 103 were hypersuccinylated/desuccinylated in ALAN-stressed moths. The hypersuccinylated/desuccinylated proteins were shown to be involved in various biological processes. In particular, they were enriched in metabolic processes, reactive oxygen species (ROS) homeostasis and the neuromuscular system. Furthermore, we demonstrated that Ksuc might affect moth locomotion by intervening with and coordinating these systems under ALAN stress. These findings suggest that Ksuc plays a vital role in the moth response to ALAN stress and moth locomotion behavior and provide a new perspective on the impact of ALAN on nocturnal insect populations and species communities.http://www.sciencedirect.com/science/article/pii/S0147651321004450Artificial light at night (ALAN)Lysine succinylation (Ksuc)MetabolismOxidative stressNeuromuscular junctionMythimna separata |
| spellingShingle | Zhijuan Huang Li He Wen Sang Lijun Wang Qiuying Huang Chaoliang Lei Potential role of lysine succinylation in the response of moths to artificial light at night stress Ecotoxicology and Environmental Safety Artificial light at night (ALAN) Lysine succinylation (Ksuc) Metabolism Oxidative stress Neuromuscular junction Mythimna separata |
| title | Potential role of lysine succinylation in the response of moths to artificial light at night stress |
| title_full | Potential role of lysine succinylation in the response of moths to artificial light at night stress |
| title_fullStr | Potential role of lysine succinylation in the response of moths to artificial light at night stress |
| title_full_unstemmed | Potential role of lysine succinylation in the response of moths to artificial light at night stress |
| title_short | Potential role of lysine succinylation in the response of moths to artificial light at night stress |
| title_sort | potential role of lysine succinylation in the response of moths to artificial light at night stress |
| topic | Artificial light at night (ALAN) Lysine succinylation (Ksuc) Metabolism Oxidative stress Neuromuscular junction Mythimna separata |
| url | http://www.sciencedirect.com/science/article/pii/S0147651321004450 |
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