Zearalenone-Induced Mechanical Damage of Intestinal Barrier via the RhoA/ROCK Signaling Pathway in IPEC-J2 Cells

Zearalenone-Induced Mechanical Damage of Intestinal Barrier via the RhoA/ROCK Signaling Pathway in IPEC-J2 Cells

Zearalenone (ZEN) is a widespread contaminant of cereals and agricultural products which causes food safety issues. Ingesting food or feed contaminated with ZEN can disrupt the intestinal epithelial barrier function. The RhoA/ROCK signaling pathway plays a key role in regulating the epithelial barri...

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Bibliographic Details
Main Authors: Biying Huang, Jingjing Wang, Aixin Gu, Tianhu Wang, Jianping Li, Anshan Shan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
zearalenone
RhoA/ROCK pathway
intestinal barrier
IPEC-J2 cells
Online Access:https://www.mdpi.com/1422-0067/23/20/12550

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