PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS
The research was conducted to study the morphological, clinical, and macroscopic characteristics of the different histological types of canine testicular tumors. The material was obtained during a routine surgery for the removal of testicular tumors in dogs in clinics of veterinary medicine in Kyiv....
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| Format: | Article |
| Language: | English |
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National University of Life and Environmental Sciences of Ukraine
2020-07-01
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| Series: | Ukrainian Journal of Veterinary Sciences |
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| Online Access: | https://veterinaryscience.com.ua/en/journals/tom-11-3-2020/patomorfologichni-osoblivosti-pukhlin-yayechok-u-sobak |
| _version_ | 1797271814465912832 |
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| author | N. B. KOLYCH |
| author_facet | N. B. KOLYCH |
| author_sort | N. B. KOLYCH |
| collection | DOAJ |
| description | The research was conducted to study the morphological, clinical, and macroscopic characteristics of the different histological types of canine testicular tumors. The material was obtained during a routine surgery for the removal of testicular tumors in dogs in clinics of veterinary medicine in Kyiv. Tumors were divided into sex cord-stromal tumors and germ cell tumors. Among the sex-cord stromal tumors recorded Leydig (interstitial) and Sertoli cell tumors. Macroscopic and histologic characteristics of canine interstitial (Leydig) cell tumor are described. It comprises 12% of all testicular tumors. Interstitial (Leydig) cell tumor has a slower growth compared to other testicular tumors, metastases are not observed. Half of the animals had no clinical signs. Most interstitial (Leydig) cell tumor go together with the pathology of adnexal structures. This is because Leydig cell tumor leads to increased levels of androgens. This fact may cause the pathology of adnexal structures. Neoplasms are recorded both on the right and the left testis. Leydig cell tumor was not related to the cryptorchid testicles. Mostly, tumors are regular oval, brown or gray color, different texture, and size with no signs of necrosis or ulceration. Macroscopic and histologic characteristics of malignant tumors of the testicle are described. A macroscopic picture was different and did not have clear meaning with the histological type of tumors. Microscopically a seminoma was characterized by the presence of layers of oval cells with the expressed grainy cytoplasm, surrounded by connective tissue, in which there was significant lymphoid infiltration. Leydig cell tumor is composed of cells that resemble Leydig cells and that are arranged into islands or tubular structures. The polygonal eosinophilic cells with granular or vacuolated, which contains lipids, were detected. Nuclei were a round mesh of chromatin and distinct nucleolus. Sometimes the large cells with 1, 2, or more nucleoli were noted. In Sertoli cell, tumor marked the various spectrum of cages from polygonal to prismatic sustenocytes |
| first_indexed | 2024-03-07T14:13:40Z |
| format | Article |
| id | doaj.art-7aef5a174d8b40a88dde13a0e7985193 |
| institution | Directory Open Access Journal |
| issn | 2663-967X 2663-9688 |
| language | English |
| last_indexed | 2024-03-07T14:13:40Z |
| publishDate | 2020-07-01 |
| publisher | National University of Life and Environmental Sciences of Ukraine |
| record_format | Article |
| series | Ukrainian Journal of Veterinary Sciences |
| spelling | doaj.art-7aef5a174d8b40a88dde13a0e79851932024-03-06T14:07:21ZengNational University of Life and Environmental Sciences of UkraineUkrainian Journal of Veterinary Sciences2663-967X2663-96882020-07-011139310110.31548/ujvs2020.03.010PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGSN. B. KOLYCH0National University of Bioresources and Nature Management of UkraineThe research was conducted to study the morphological, clinical, and macroscopic characteristics of the different histological types of canine testicular tumors. The material was obtained during a routine surgery for the removal of testicular tumors in dogs in clinics of veterinary medicine in Kyiv. Tumors were divided into sex cord-stromal tumors and germ cell tumors. Among the sex-cord stromal tumors recorded Leydig (interstitial) and Sertoli cell tumors. Macroscopic and histologic characteristics of canine interstitial (Leydig) cell tumor are described. It comprises 12% of all testicular tumors. Interstitial (Leydig) cell tumor has a slower growth compared to other testicular tumors, metastases are not observed. Half of the animals had no clinical signs. Most interstitial (Leydig) cell tumor go together with the pathology of adnexal structures. This is because Leydig cell tumor leads to increased levels of androgens. This fact may cause the pathology of adnexal structures. Neoplasms are recorded both on the right and the left testis. Leydig cell tumor was not related to the cryptorchid testicles. Mostly, tumors are regular oval, brown or gray color, different texture, and size with no signs of necrosis or ulceration. Macroscopic and histologic characteristics of malignant tumors of the testicle are described. A macroscopic picture was different and did not have clear meaning with the histological type of tumors. Microscopically a seminoma was characterized by the presence of layers of oval cells with the expressed grainy cytoplasm, surrounded by connective tissue, in which there was significant lymphoid infiltration. Leydig cell tumor is composed of cells that resemble Leydig cells and that are arranged into islands or tubular structures. The polygonal eosinophilic cells with granular or vacuolated, which contains lipids, were detected. Nuclei were a round mesh of chromatin and distinct nucleolus. Sometimes the large cells with 1, 2, or more nucleoli were noted. In Sertoli cell, tumor marked the various spectrum of cages from polygonal to prismatic sustenocyteshttps://veterinaryscience.com.ua/en/journals/tom-11-3-2020/patomorfologichni-osoblivosti-pukhlin-yayechok-u-sobaknon-germ cell tumorsgenital stromal tumorsbenign tumorsleydig cell tumorsertoliomaseminomatesticular neoplasmsdogs |
| spellingShingle | N. B. KOLYCH PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS Ukrainian Journal of Veterinary Sciences non-germ cell tumors genital stromal tumors benign tumors leydig cell tumor sertolioma seminoma testicular neoplasms dogs |
| title | PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS |
| title_full | PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS |
| title_fullStr | PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS |
| title_full_unstemmed | PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS |
| title_short | PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS |
| title_sort | pathomorphological features of testicular tumors in dogs |
| topic | non-germ cell tumors genital stromal tumors benign tumors leydig cell tumor sertolioma seminoma testicular neoplasms dogs |
| url | https://veterinaryscience.com.ua/en/journals/tom-11-3-2020/patomorfologichni-osoblivosti-pukhlin-yayechok-u-sobak |
| work_keys_str_mv | AT nbkolych pathomorphologicalfeaturesoftesticulartumorsindogs |