Scribble basal polarity acquisition in RPE cells and its mislocalization in a pathological AMD-like model

Scribble basal polarity acquisition in RPE cells and its mislocalization in a pathological AMD-like model

Apicobasal polarity is a hallmark of retinal pigment epithelium cells and is required to perform their functions; however, the precise roles of the different proteins that execute polarity are still poorly understood. Here, we have studied the expression and location of Scribble, the core member of...

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Bibliographic Details
Main Authors: Alicia Segurado, Alba Rodríguez-Carrillo, Bárbara Castellanos, Emiliano Hernández-Galilea, Almudena Velasco, Concepción Lillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroanatomy
Subjects:
Scribble
cell polarity
epithelium
differentiation
retina
retinal pigment epithelium (RPE)
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2022.983151/full

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