Transcriptional Spatial Profiling of Cancer Tissues in the Era of Immunotherapy: The Potential and Promise

Transcriptional Spatial Profiling of Cancer Tissues in the Era of Immunotherapy: The Potential and Promise

Intratumoral heterogeneity poses a major challenge to making an accurate diagnosis and establishing personalized treatment strategies for cancer patients. Moreover, this heterogeneity might underlie treatment resistance, disease progression, and cancer relapse. For example, while immunotherapies can...

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Bibliographic Details
Main Authors: Sanjna Nilesh Nerurkar, Denise Goh, Chun Chau Lawrence Cheung, Pei Qi Yvonne Nga, Jeffrey Chun Tatt Lim, Joe Poh Sheng Yeong
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
heterogeneity
clonal diversity
transcriptomics
in situ hybridization
digital spatial profiling
cancer
Online Access:https://www.mdpi.com/2072-6694/12/9/2572

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