Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering.

Generation of Knock-In Pigs Carrying Oct4-tdTomato Reporter through CRISPR/Cas9-Mediated Genome Engineering.

The porcine pluripotent cells that can generate germline chimeras have not been developed. The Oct4 promoter-based fluorescent reporter system, which can be used to monitor pluripotency, is an important tool to generate authentic porcine pluripotent cells. In this study, we established a porcine Oct...

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Bibliographic Details
Main Authors: Sisi Lai, Shu Wei, Bentian Zhao, Zhen Ouyang, Quanjun Zhang, Nana Fan, Zhaoming Liu, Yu Zhao, Quanmei Yan, Xiaoqing Zhou, Li Li, Jige Xin, Yangzhi Zeng, Liangxue Lai, Qingjian Zou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4710570?pdf=render

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