Dry Eye and Meibomian Glands in Vitiligo
Objectives:To evaluate aqueous and lipid tear film parameters and the meibomian glands (MGs) with non-contact meibography in patients with vitiligo.Materials and Methods:This case-control study was conducted in the right (OD) and left (OS) eyes of 43 patients with vitiligo and 43 controls in Birjand...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2021-04-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/dry-eye-and-meibomian-glands-in-vitiligo/47342
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| _version_ | 1797906386605047808 |
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| author | Ahmad Reza Taheri Elahe Allahyari Borhan Haghi Rudi Malihe Nikandish |
| author_facet | Ahmad Reza Taheri Elahe Allahyari Borhan Haghi Rudi Malihe Nikandish |
| author_sort | Ahmad Reza Taheri |
| collection | DOAJ |
| description | Objectives:To evaluate aqueous and lipid tear film parameters and the meibomian glands (MGs) with non-contact meibography in patients with vitiligo.Materials and Methods:This case-control study was conducted in the right (OD) and left (OS) eyes of 43 patients with vitiligo and 43 controls in Birjand, Iran. In addition to demographic information and skin disease characteristics, the Ocular Surface Disease Index (OSDI) questionnaire was completed for each patient, followed by eye examinations including slit lamp examination, Schirmer test, strip meniscometry (SMTube), and tear break-up time (TBUT) measurement. The MGs were also imaged using a non-contact meibography system (SBM System, Italy). The data were analyzed using SPSS version 22.0 with a significant level of less than 0.05.Results:Patients had higher OSDI score than controls but it was not significant (10.90±13.03 vs. 5.57±6.85; p=0.07). There were significant differences between the groups in mean Schirmer test values for both eyes (OD: 8.07±5.47 vs. 17.37±6.52; OS: 7.60±5.00 vs. 17.30±6.44, p<0.001) and mean SMTube results (OD: 4.49±2.40 vs. 9.74±3.67; OS: 4.30±2.81 vs. 9.65±4.52; p<0.001). However, mean TBUT did not differ between the groups (OD: 9.14±3.17 vs. 10.12±2.08, p=0.27; OS: 9.16±3.30 vs. 10.05±2.10, p=0.25). Meibography also showed no significant difference in MG dropout between the groups (OD: 20.86±9.79 vs. 21.05±12.07; p=0.74; OS: 18.16±8.83 vs. 19.53±10.30; p=0.51).Conclusion:Vitiligo is associated with a reduction in the production of aqueous tear film, but does not affect the structure and function of the MGs. |
| first_indexed | 2024-04-10T10:20:06Z |
| format | Article |
| id | doaj.art-7af70958d0734cbfb8f70ae03ec36e3b |
| institution | Directory Open Access Journal |
| issn | 1300-0659 2147-2661 |
| language | English |
| last_indexed | 2024-04-10T10:20:06Z |
| publishDate | 2021-04-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Oftalmoloji Dergisi |
| spelling | doaj.art-7af70958d0734cbfb8f70ae03ec36e3b2023-02-15T16:21:39ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612021-04-01512707410.4274/tjo.galenos.2020.7802713049054Dry Eye and Meibomian Glands in VitiligoAhmad Reza Taheri0Elahe Allahyari1Borhan Haghi Rudi2Malihe Nikandish3 Meşhed Tıp Bilimleri Üniversitesi, Kutanöz Leishmaniasis Araştırma Merkezi, Meşhed, İran Birjand Tıp Bilimleri Üniversitesi Sağlık Yüksekokulu, Epidemiyoloji ve Biyoistatistik Anabilim Dalı, Sağlık Araştırma Merkezinin Sosyal Belirleyicileri, Birjand, İran Birjand Tıp Bilimleri Üniversitesi Valiasr Hastanesi, Göz Hastalıkları Anabilim Dalı, Birjand, İran Birjand Tıp Bilimleri Üniversitesi Valiasr Hastanesi, Göz Hastalıkları Anabilim Dalı, Birjand, İran Objectives:To evaluate aqueous and lipid tear film parameters and the meibomian glands (MGs) with non-contact meibography in patients with vitiligo.Materials and Methods:This case-control study was conducted in the right (OD) and left (OS) eyes of 43 patients with vitiligo and 43 controls in Birjand, Iran. In addition to demographic information and skin disease characteristics, the Ocular Surface Disease Index (OSDI) questionnaire was completed for each patient, followed by eye examinations including slit lamp examination, Schirmer test, strip meniscometry (SMTube), and tear break-up time (TBUT) measurement. The MGs were also imaged using a non-contact meibography system (SBM System, Italy). The data were analyzed using SPSS version 22.0 with a significant level of less than 0.05.Results:Patients had higher OSDI score than controls but it was not significant (10.90±13.03 vs. 5.57±6.85; p=0.07). There were significant differences between the groups in mean Schirmer test values for both eyes (OD: 8.07±5.47 vs. 17.37±6.52; OS: 7.60±5.00 vs. 17.30±6.44, p<0.001) and mean SMTube results (OD: 4.49±2.40 vs. 9.74±3.67; OS: 4.30±2.81 vs. 9.65±4.52; p<0.001). However, mean TBUT did not differ between the groups (OD: 9.14±3.17 vs. 10.12±2.08, p=0.27; OS: 9.16±3.30 vs. 10.05±2.10, p=0.25). Meibography also showed no significant difference in MG dropout between the groups (OD: 20.86±9.79 vs. 21.05±12.07; p=0.74; OS: 18.16±8.83 vs. 19.53±10.30; p=0.51).Conclusion:Vitiligo is associated with a reduction in the production of aqueous tear film, but does not affect the structure and function of the MGs. http://www.oftalmoloji.org/archives/archive-detail/article-preview/dry-eye-and-meibomian-glands-in-vitiligo/47342 vitiligodry eyemeibomian glands |
| spellingShingle | Ahmad Reza Taheri Elahe Allahyari Borhan Haghi Rudi Malihe Nikandish Dry Eye and Meibomian Glands in Vitiligo Türk Oftalmoloji Dergisi vitiligo dry eye meibomian glands |
| title | Dry Eye and Meibomian Glands in Vitiligo |
| title_full | Dry Eye and Meibomian Glands in Vitiligo |
| title_fullStr | Dry Eye and Meibomian Glands in Vitiligo |
| title_full_unstemmed | Dry Eye and Meibomian Glands in Vitiligo |
| title_short | Dry Eye and Meibomian Glands in Vitiligo |
| title_sort | dry eye and meibomian glands in vitiligo |
| topic | vitiligo dry eye meibomian glands |
| url |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/dry-eye-and-meibomian-glands-in-vitiligo/47342
|
| work_keys_str_mv | AT ahmadrezataheri dryeyeandmeibomianglandsinvitiligo AT elaheallahyari dryeyeandmeibomianglandsinvitiligo AT borhanhaghirudi dryeyeandmeibomianglandsinvitiligo AT malihenikandish dryeyeandmeibomianglandsinvitiligo |