Cx32 exerts anti-apoptotic and pro-tumor effects via the epidermal growth factor receptor pathway in hepatocellular carcinoma

Cx32 exerts anti-apoptotic and pro-tumor effects via the epidermal growth factor receptor pathway in hepatocellular carcinoma

Abstract Background Abnormal expression or distribution of connexin 32 (Cx32) is associated with hepatocarcinogenesis, but the role of Cx32 and the underlying mechanisms are still unclear. Methods The expression level of Cx32 in 96 hepatocellular carcinoma (HCC) specimens was determined using wester...

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Bibliographic Details
Main Authors: Yuke Xiang, Qin Wang, Yunquan Guo, Hui Ge, Yile Fu, Xiyan Wang, Liang Tao
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Connexin32
Hepatocellular carcinoma
Apoptosis
EGFR
Src
Nonjunctional function
Online Access:http://link.springer.com/article/10.1186/s13046-019-1142-y

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