Value and choice as separable and stable representations in orbitofrontal cortex
In value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times.
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2020-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-17058-y |
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author | Daniel L. Kimmel Gamaleldin F. Elsayed John P. Cunningham William T. Newsome |
author_facet | Daniel L. Kimmel Gamaleldin F. Elsayed John P. Cunningham William T. Newsome |
author_sort | Daniel L. Kimmel |
collection | DOAJ |
description | In value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times. |
first_indexed | 2024-12-20T21:43:32Z |
format | Article |
id | doaj.art-7afb464fd13c4274a79e5d98bdb14f97 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-20T21:43:32Z |
publishDate | 2020-07-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-7afb464fd13c4274a79e5d98bdb14f972022-12-21T19:25:44ZengNature PortfolioNature Communications2041-17232020-07-0111111910.1038/s41467-020-17058-yValue and choice as separable and stable representations in orbitofrontal cortexDaniel L. Kimmel0Gamaleldin F. Elsayed1John P. Cunningham2William T. Newsome3Mortimer Zuckerman Mind Brain Behavior Institute, Columbia UniversityGoogle Research, Brain TeamMortimer Zuckerman Mind Brain Behavior Institute, Columbia UniversityDepartment of Neurobiology and Wu Tsai Neurosciences Institute, Stanford UniversityIn value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times.https://doi.org/10.1038/s41467-020-17058-y |
spellingShingle | Daniel L. Kimmel Gamaleldin F. Elsayed John P. Cunningham William T. Newsome Value and choice as separable and stable representations in orbitofrontal cortex Nature Communications |
title | Value and choice as separable and stable representations in orbitofrontal cortex |
title_full | Value and choice as separable and stable representations in orbitofrontal cortex |
title_fullStr | Value and choice as separable and stable representations in orbitofrontal cortex |
title_full_unstemmed | Value and choice as separable and stable representations in orbitofrontal cortex |
title_short | Value and choice as separable and stable representations in orbitofrontal cortex |
title_sort | value and choice as separable and stable representations in orbitofrontal cortex |
url | https://doi.org/10.1038/s41467-020-17058-y |
work_keys_str_mv | AT daniellkimmel valueandchoiceasseparableandstablerepresentationsinorbitofrontalcortex AT gamaleldinfelsayed valueandchoiceasseparableandstablerepresentationsinorbitofrontalcortex AT johnpcunningham valueandchoiceasseparableandstablerepresentationsinorbitofrontalcortex AT williamtnewsome valueandchoiceasseparableandstablerepresentationsinorbitofrontalcortex |