Value and choice as separable and stable representations in orbitofrontal cortex

In value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times.

Bibliographic Details
Main Authors: Daniel L. Kimmel, Gamaleldin F. Elsayed, John P. Cunningham, William T. Newsome
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17058-y
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author Daniel L. Kimmel
Gamaleldin F. Elsayed
John P. Cunningham
William T. Newsome
author_facet Daniel L. Kimmel
Gamaleldin F. Elsayed
John P. Cunningham
William T. Newsome
author_sort Daniel L. Kimmel
collection DOAJ
description In value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times.
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spelling doaj.art-7afb464fd13c4274a79e5d98bdb14f972022-12-21T19:25:44ZengNature PortfolioNature Communications2041-17232020-07-0111111910.1038/s41467-020-17058-yValue and choice as separable and stable representations in orbitofrontal cortexDaniel L. Kimmel0Gamaleldin F. Elsayed1John P. Cunningham2William T. Newsome3Mortimer Zuckerman Mind Brain Behavior Institute, Columbia UniversityGoogle Research, Brain TeamMortimer Zuckerman Mind Brain Behavior Institute, Columbia UniversityDepartment of Neurobiology and Wu Tsai Neurosciences Institute, Stanford UniversityIn value-based decision-making, single prefrontal neurons represent multiple variables at different times in the decision process. Here, the authors show these representations to be separable and stable at the population level, allowing read out of specific variables at behaviorally relevant times.https://doi.org/10.1038/s41467-020-17058-y
spellingShingle Daniel L. Kimmel
Gamaleldin F. Elsayed
John P. Cunningham
William T. Newsome
Value and choice as separable and stable representations in orbitofrontal cortex
Nature Communications
title Value and choice as separable and stable representations in orbitofrontal cortex
title_full Value and choice as separable and stable representations in orbitofrontal cortex
title_fullStr Value and choice as separable and stable representations in orbitofrontal cortex
title_full_unstemmed Value and choice as separable and stable representations in orbitofrontal cortex
title_short Value and choice as separable and stable representations in orbitofrontal cortex
title_sort value and choice as separable and stable representations in orbitofrontal cortex
url https://doi.org/10.1038/s41467-020-17058-y
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AT williamtnewsome valueandchoiceasseparableandstablerepresentationsinorbitofrontalcortex