Non-linear label-free imaging through a multimode graded index optical fibre
In recent years, great advances have been made in developing minimal footprint micro-endoscopes using multimode optical fibres (MMF) [1]. By employing wavefront shaping methods the seemingly random speckle pattern resulting from the guiding of coherent light through an MMF can be formed into a diffr...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2020-01-01
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| Series: | EPJ Web of Conferences |
| Online Access: | https://www.epj-conferences.org/articles/epjconf/pdf/2020/14/epjconf_eosam2020_04006.pdf |
| Summary: | In recent years, great advances have been made in developing minimal footprint micro-endoscopes using multimode optical fibres (MMF) [1]. By employing wavefront shaping methods the seemingly random speckle pattern resulting from the guiding of coherent light through an MMF can be formed into a diffraction limited spot. This enables the implementation of multiple laser scanning techniques. In this work we show that this approach can be employed to realize label-free non-linear microscopy techniques such as coherent anti-Stokes Raman scattering (CARS) and second harmonic generation (SHG). Backscattered light makes epi-detection possible even though these processes preferably emit light in the direction of beam propagation [2]. |
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| ISSN: | 2100-014X |