Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a public health concern worldwide, but comprehensive analysis of risk factors for CRPA remains limited in China. We conducted a retrospective observational study of carbapenem resistance in 71,880 P. aeruginosa isolates collected in Zhejiang Prov...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2019-10-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/25/10/18-1699_article |
| _version_ | 1818318788305616896 |
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| author | Yan-Yan Hu Jun-Min Cao Qing Yang Shi Chen Huo-Yang Lv Hong-Wei Zhou Zuowei Wu Rong Zhang |
| author_facet | Yan-Yan Hu Jun-Min Cao Qing Yang Shi Chen Huo-Yang Lv Hong-Wei Zhou Zuowei Wu Rong Zhang |
| author_sort | Yan-Yan Hu |
| collection | DOAJ |
| description | Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a public health concern worldwide, but comprehensive analysis of risk factors for CRPA remains limited in China. We conducted a retrospective observational study of carbapenem resistance in 71,880 P. aeruginosa isolates collected in Zhejiang Province during 2015–2017. We analyzed risk factors for CRPA, including the type of clinical specimen; the year, season, and region in which it was collected; patient information, including age, whether they were an outpatient or inpatient, and whether inpatients were in the intensive care unit or general ward; and the level of hospital submitting isolates. We found CRPA was more prevalent among isolates from patients >60 years of age and in inpatients, especially in intensive care units. In addition, specimen types and seasons in which they were collected were associated with higher rates of CRPA. Our findings can help hospitals reduce the spread of P. aeruginosa and optimize antimicrobial drug use. |
| first_indexed | 2024-12-13T09:58:47Z |
| format | Article |
| id | doaj.art-7afd53e9512f4d769102bdc95a3c2812 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-13T09:58:47Z |
| publishDate | 2019-10-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-7afd53e9512f4d769102bdc95a3c28122022-12-21T23:51:42ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-10-0125101861186710.3201/eid2510.181699Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, ChinaYan-Yan HuJun-Min CaoQing YangShi ChenHuo-Yang LvHong-Wei ZhouZuowei WuRong ZhangCarbapenem-resistant Pseudomonas aeruginosa (CRPA) is a public health concern worldwide, but comprehensive analysis of risk factors for CRPA remains limited in China. We conducted a retrospective observational study of carbapenem resistance in 71,880 P. aeruginosa isolates collected in Zhejiang Province during 2015–2017. We analyzed risk factors for CRPA, including the type of clinical specimen; the year, season, and region in which it was collected; patient information, including age, whether they were an outpatient or inpatient, and whether inpatients were in the intensive care unit or general ward; and the level of hospital submitting isolates. We found CRPA was more prevalent among isolates from patients >60 years of age and in inpatients, especially in intensive care units. In addition, specimen types and seasons in which they were collected were associated with higher rates of CRPA. Our findings can help hospitals reduce the spread of P. aeruginosa and optimize antimicrobial drug use.https://wwwnc.cdc.gov/eid/article/25/10/18-1699_articleCarbapenemrisk factorsPseudomonas aeruginosabacteriaantimicrobial resistancesurveillance |
| spellingShingle | Yan-Yan Hu Jun-Min Cao Qing Yang Shi Chen Huo-Yang Lv Hong-Wei Zhou Zuowei Wu Rong Zhang Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China Emerging Infectious Diseases Carbapenem risk factors Pseudomonas aeruginosa bacteria antimicrobial resistance surveillance |
| title | Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China |
| title_full | Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China |
| title_fullStr | Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China |
| title_full_unstemmed | Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China |
| title_short | Risk Factors for Carbapenem-Resistant Pseudomonas aeruginosa, Zhejiang Province, China |
| title_sort | risk factors for carbapenem resistant pseudomonas aeruginosa zhejiang province china |
| topic | Carbapenem risk factors Pseudomonas aeruginosa bacteria antimicrobial resistance surveillance |
| url | https://wwwnc.cdc.gov/eid/article/25/10/18-1699_article |
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