Individual Vulnerability to Stress Is Associated With Increased Demand for Intravenous Heroin Self-administration in Rats
Opioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating individual differences underlying stress reacti...
Main Authors: | Nathaniel P. Stafford, Theodore N. Kazan, Colleen M. Donovan, Erin E. Hart, Robert C. Drugan, Sergios Charntikov |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-06-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnbeh.2019.00134/full |
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