Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox
Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron ch...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-09-01
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| Series: | Hematology Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/hr/article/view/5987 |
| _version_ | 1797935975976927232 |
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| author | Galina Ling Vered Pinsk Inbal Golan-Tripto Eduard Ling |
| author_facet | Galina Ling Vered Pinsk Inbal Golan-Tripto Eduard Ling |
| author_sort | Galina Ling |
| collection | DOAJ |
| description | Congenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment. |
| first_indexed | 2024-04-10T18:22:24Z |
| format | Article |
| id | doaj.art-7b03974d458c46f9ad519288643089f9 |
| institution | Directory Open Access Journal |
| issn | 2038-8322 2038-8330 |
| language | English |
| last_indexed | 2024-04-10T18:22:24Z |
| publishDate | 2015-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Hematology Reports |
| spelling | doaj.art-7b03974d458c46f9ad519288643089f92023-02-02T06:57:54ZengMDPI AGHematology Reports2038-83222038-83302015-09-017310.4081/hr.2015.59873160Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasiroxGalina Ling0Vered Pinsk1Inbal Golan-Tripto2Eduard Ling3Pediatric Gastroenterology and Nutrition Unit, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Beer ShevaPediatric Gastroenterology and Nutrition Unit, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Beer ShevaPediatrics Department B, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Beer ShevaPediatrics Department B, Saban Pediatric Medical Center for Israel, Soroka University Medical Center, Beer ShevaCongenital dyserythropoietic anemias (CDA) represent a heterogeneous group of disorders characterized by morphological abnormalities of erythroid precursor cells and various degrees of hemolysis. Iron overload is a result of continuous hemolysis and recurrent transfusions. It is treated with iron chelators, including deferasirox. We present here a case of acute liver failure in a 12 years old girl with CDA type I treated with deferasirox and discuss the approach to treatment.http://www.pagepress.org/journals/index.php/hr/article/view/5987Congenital dyserythropoietic anemiadeferasiroxacute liver failureN-acetylcysteine |
| spellingShingle | Galina Ling Vered Pinsk Inbal Golan-Tripto Eduard Ling Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox Hematology Reports Congenital dyserythropoietic anemia deferasirox acute liver failure N-acetylcysteine |
| title | Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox |
| title_full | Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox |
| title_fullStr | Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox |
| title_full_unstemmed | Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox |
| title_short | Acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type I treated with deferasirox |
| title_sort | acute liver failure in a pediatric patient with congenital dyserythropoietic anemia type i treated with deferasirox |
| topic | Congenital dyserythropoietic anemia deferasirox acute liver failure N-acetylcysteine |
| url | http://www.pagepress.org/journals/index.php/hr/article/view/5987 |
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