Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective
ABSTRACT The oral microbiota is enormously diverse, with over 700 microbial species identified across individuals that play a vital role in the health of our mouth and our overall well-being. In addition, as oral diseases such as caries (cavities) and periodontitis (gum disease) are mediated through...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2022-06-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.00235-22 |
| _version_ | 1818249303130374144 |
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| author | Mengshi Zhang Marvin Whiteley Gina R. Lewin |
| author_facet | Mengshi Zhang Marvin Whiteley Gina R. Lewin |
| author_sort | Mengshi Zhang |
| collection | DOAJ |
| description | ABSTRACT The oral microbiota is enormously diverse, with over 700 microbial species identified across individuals that play a vital role in the health of our mouth and our overall well-being. In addition, as oral diseases such as caries (cavities) and periodontitis (gum disease) are mediated through interspecies microbial interactions, this community serves as an important model system to study the complexity and dynamics of polymicrobial interactions. Here, we review historical and recent progress in our understanding of the oral microbiome, highlighting how oral microbiome research has significantly contributed to our understanding of microbial communities, with broad implications in polymicrobial diseases and across microbial community ecology. Further, we explore innovations and challenges associated with analyzing polymicrobial systems and suggest future directions of study. Finally, we provide a conceptual framework to systematically study microbial interactions within complex communities, not limited to the oral microbiota. |
| first_indexed | 2024-12-12T15:34:21Z |
| format | Article |
| id | doaj.art-7b0501d7f55a4c458465d503f43469f8 |
| institution | Directory Open Access Journal |
| issn | 2150-7511 |
| language | English |
| last_indexed | 2024-12-12T15:34:21Z |
| publishDate | 2022-06-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mBio |
| spelling | doaj.art-7b0501d7f55a4c458465d503f43469f82022-12-22T00:20:03ZengAmerican Society for MicrobiologymBio2150-75112022-06-0113310.1128/mbio.00235-22Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current PerspectiveMengshi Zhang0Marvin Whiteley1Gina R. Lewin2School of Biological Sciences and Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USASchool of Biological Sciences and Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USASchool of Biological Sciences and Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USAABSTRACT The oral microbiota is enormously diverse, with over 700 microbial species identified across individuals that play a vital role in the health of our mouth and our overall well-being. In addition, as oral diseases such as caries (cavities) and periodontitis (gum disease) are mediated through interspecies microbial interactions, this community serves as an important model system to study the complexity and dynamics of polymicrobial interactions. Here, we review historical and recent progress in our understanding of the oral microbiome, highlighting how oral microbiome research has significantly contributed to our understanding of microbial communities, with broad implications in polymicrobial diseases and across microbial community ecology. Further, we explore innovations and challenges associated with analyzing polymicrobial systems and suggest future directions of study. Finally, we provide a conceptual framework to systematically study microbial interactions within complex communities, not limited to the oral microbiota.https://journals.asm.org/doi/10.1128/mbio.00235-22microbiomemicrobe-microbe interactionsmicrobial ecologyoral microbiology |
| spellingShingle | Mengshi Zhang Marvin Whiteley Gina R. Lewin Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective mBio microbiome microbe-microbe interactions microbial ecology oral microbiology |
| title | Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective |
| title_full | Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective |
| title_fullStr | Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective |
| title_full_unstemmed | Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective |
| title_short | Polymicrobial Interactions of Oral Microbiota: a Historical Review and Current Perspective |
| title_sort | polymicrobial interactions of oral microbiota a historical review and current perspective |
| topic | microbiome microbe-microbe interactions microbial ecology oral microbiology |
| url | https://journals.asm.org/doi/10.1128/mbio.00235-22 |
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