Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686
Paracoccus aminophilus JCM 7686 (Alphaproteobacteria) is a facultative, heterotrophic methylotroph capable of utilizing a wide range of C1 compounds as sole carbon and energy sources. Analysis of the JCM 7686 genome revealed the presence of genes involved in the oxidation of methanol, methylamine, d...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-08-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00852/full |
| _version_ | 1819136387206610944 |
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| author | Lukasz eDziewit Jakub eCzarnecki Emilia eProchwicz Daniel eWibberg Andreas eSchlüter Alfred ePühler Dariusz eBartosik |
| author_facet | Lukasz eDziewit Jakub eCzarnecki Emilia eProchwicz Daniel eWibberg Andreas eSchlüter Alfred ePühler Dariusz eBartosik |
| author_sort | Lukasz eDziewit |
| collection | DOAJ |
| description | Paracoccus aminophilus JCM 7686 (Alphaproteobacteria) is a facultative, heterotrophic methylotroph capable of utilizing a wide range of C1 compounds as sole carbon and energy sources. Analysis of the JCM 7686 genome revealed the presence of genes involved in the oxidation of methanol, methylamine, dimethylamine, trimethylamine, N,N-dimethylformamide and formamide, as well as the serine cycle, which appears to be the only C1 assimilatory pathway in this strain. Many of these genes are located in different extrachromosomal replicons and are not present in the genomes of most members of the genus Paracoccus, which strongly suggests that they have been horizontally acquired. When compared with Paracoccus denitrificans Pd1222 (type strain of the genus Paracoccus), P. aminophilus JCM 7686 has many additional methylotrophic capabilities (oxidation of dimethylamine, trimethylamine, N,N-dimethylformamide, the serine cycle), which are determined by the presence of three separate gene clusters. Interestingly, related clusters form compact methylotrophy islands within the genomes of Paracoccus sp. N5 and many marine bacteria of the Roseobacter clade. |
| first_indexed | 2024-12-22T10:34:10Z |
| format | Article |
| id | doaj.art-7b057996da804c33835b174d4e38938d |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-22T10:34:10Z |
| publishDate | 2015-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-7b057996da804c33835b174d4e38938d2022-12-21T18:29:14ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2015-08-01610.3389/fmicb.2015.00852147261Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686Lukasz eDziewit0Jakub eCzarnecki1Emilia eProchwicz2Daniel eWibberg3Andreas eSchlüter4Alfred ePühler5Dariusz eBartosik6Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw Department of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw Institute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld UniversityInstitute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld UniversityInstitute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld UniversityDepartment of Bacterial Genetics, Institute of Microbiology, Faculty of Biology, University of Warsaw Paracoccus aminophilus JCM 7686 (Alphaproteobacteria) is a facultative, heterotrophic methylotroph capable of utilizing a wide range of C1 compounds as sole carbon and energy sources. Analysis of the JCM 7686 genome revealed the presence of genes involved in the oxidation of methanol, methylamine, dimethylamine, trimethylamine, N,N-dimethylformamide and formamide, as well as the serine cycle, which appears to be the only C1 assimilatory pathway in this strain. Many of these genes are located in different extrachromosomal replicons and are not present in the genomes of most members of the genus Paracoccus, which strongly suggests that they have been horizontally acquired. When compared with Paracoccus denitrificans Pd1222 (type strain of the genus Paracoccus), P. aminophilus JCM 7686 has many additional methylotrophic capabilities (oxidation of dimethylamine, trimethylamine, N,N-dimethylformamide, the serine cycle), which are determined by the presence of three separate gene clusters. Interestingly, related clusters form compact methylotrophy islands within the genomes of Paracoccus sp. N5 and many marine bacteria of the Roseobacter clade.http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00852/fullDimethylformamideMethanolMethylotrophyPlasmidSerine cycleDimethylamine |
| spellingShingle | Lukasz eDziewit Jakub eCzarnecki Emilia eProchwicz Daniel eWibberg Andreas eSchlüter Alfred ePühler Dariusz eBartosik Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 Frontiers in Microbiology Dimethylformamide Methanol Methylotrophy Plasmid Serine cycle Dimethylamine |
| title | Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 |
| title_full | Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 |
| title_fullStr | Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 |
| title_full_unstemmed | Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 |
| title_short | Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 |
| title_sort | genome guided insight into the methylotrophy of paracoccus aminophilus jcm 7686 |
| topic | Dimethylformamide Methanol Methylotrophy Plasmid Serine cycle Dimethylamine |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00852/full |
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