Neoadjuvant Chemotherapy of Patients with Early Breast Cancer Is Associated with Increased Detection of Disseminated Tumor Cells in the Bone Marrow

Neoadjuvant Chemotherapy of Patients with Early Breast Cancer Is Associated with Increased Detection of Disseminated Tumor Cells in the Bone Marrow

Preclinical data suggest that neoadjuvant chemotherapy (NAT) may promote micrometastatic spread. We aimed to compare the detection rate and prognostic relevance of disseminated tumor cells (DTCs) from the bone marrow (BM) of patients with early-stage breast cancer (EBC) after NAT with that of therap...

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Bibliographic Details
Main Authors: Léa Volmer, André Koch, Sabine Matovina, Dominik Dannehl, Martin Weiss, Ganna Welker, Markus Hahn, Tobias Engler, Markus Wallwiener, Christina Barbara Walter, Ernst Oberlechner, Sara Yvonne Brucker, Klaus Pantel, Andreas Hartkopf
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
breast cancer
disseminated tumor cells
neoadjuvant chemotherapy
circulating tumor cells
Online Access:https://www.mdpi.com/2072-6694/14/3/635

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