Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of...
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2005-04-01
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| Series: | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
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| Online Access: | http://jbums.org/article-1-2636-en.html |
| _version_ | 1818684170360061952 |
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| author | MJ Golali Pour S Mohammadian MH Taziki E Mobasheri A Borghei |
| author_facet | MJ Golali Pour S Mohammadian MH Taziki E Mobasheri A Borghei |
| author_sort | MJ Golali Pour |
| collection | DOAJ |
| description | Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of cleft lip and palate and its relation with sex, ethnic group, paternal and maternal age, consanguineous marriage and season in Gorgan during 6 years. Methods: This cross-sectional study was done on 37951 births in Gorgan’s Dezyani hospital during 1998-2003. Sex, type of abnormalities, ethnic group, paternal and maternal age, consanguineous marriage, season and date of birth were recorded in questionnaires and data were analyzed by SPSS. Findings: The prevalence of cleft lip and cleft palate was 0.97 per 1000 birth and it was more common in males (1.08 per 1000) than in females (0.86 per 1000). The rate of cleft was 0.86, 0.89 and 1.47 per 1000 in native Fars, Turkaman and Sistani ethnic group, respectively. 29.7% of parents had consanguineous marriage. 29.7% of mothers with affected newborns consumed different drugs during pregnancy. The commonest rate was in winter and autumn. Maternal and paternal age was 35.5 and 28.5 years, respectively. Cleft was more common in 1998. Conclusion: This study reveals that incidence of cleft in Gorgan is much closer to European and east Asian countries. Consanguineous marriage and the toxicity of pregnant women with drugs or chemicals can induce cleft palate. |
| first_indexed | 2024-12-17T10:46:22Z |
| format | Article |
| id | doaj.art-7b0a737595f546919a0f4c35b411f4a4 |
| institution | Directory Open Access Journal |
| issn | 1561-4107 2251-7170 |
| language | English |
| last_indexed | 2024-12-17T10:46:22Z |
| publishDate | 2005-04-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul |
| spelling | doaj.art-7b0a737595f546919a0f4c35b411f4a42022-12-21T21:52:07ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702005-04-01724147Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003MJ Golali Pour0S Mohammadian1MH Taziki2E Mobasheri3A Borghei4 Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of cleft lip and palate and its relation with sex, ethnic group, paternal and maternal age, consanguineous marriage and season in Gorgan during 6 years. Methods: This cross-sectional study was done on 37951 births in Gorgan’s Dezyani hospital during 1998-2003. Sex, type of abnormalities, ethnic group, paternal and maternal age, consanguineous marriage, season and date of birth were recorded in questionnaires and data were analyzed by SPSS. Findings: The prevalence of cleft lip and cleft palate was 0.97 per 1000 birth and it was more common in males (1.08 per 1000) than in females (0.86 per 1000). The rate of cleft was 0.86, 0.89 and 1.47 per 1000 in native Fars, Turkaman and Sistani ethnic group, respectively. 29.7% of parents had consanguineous marriage. 29.7% of mothers with affected newborns consumed different drugs during pregnancy. The commonest rate was in winter and autumn. Maternal and paternal age was 35.5 and 28.5 years, respectively. Cleft was more common in 1998. Conclusion: This study reveals that incidence of cleft in Gorgan is much closer to European and east Asian countries. Consanguineous marriage and the toxicity of pregnant women with drugs or chemicals can induce cleft palate.http://jbums.org/article-1-2636-en.htmlcleft lipcleft palateepidemiologyethnicitysex |
| spellingShingle | MJ Golali Pour S Mohammadian MH Taziki E Mobasheri A Borghei Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul cleft lip cleft palate epidemiology ethnicity sex |
| title | Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 |
| title_full | Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 |
| title_fullStr | Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 |
| title_full_unstemmed | Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 |
| title_short | Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003 |
| title_sort | epidemiology of cleft lip and cleft palate in gorgan 1998 2003 |
| topic | cleft lip cleft palate epidemiology ethnicity sex |
| url | http://jbums.org/article-1-2636-en.html |
| work_keys_str_mv | AT mjgolalipour epidemiologyofcleftlipandcleftpalateingorgan19982003 AT smohammadian epidemiologyofcleftlipandcleftpalateingorgan19982003 AT mhtaziki epidemiologyofcleftlipandcleftpalateingorgan19982003 AT emobasheri epidemiologyofcleftlipandcleftpalateingorgan19982003 AT aborghei epidemiologyofcleftlipandcleftpalateingorgan19982003 |