The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration
Hydrogels based on various polymeric materials have been successfully developed in recent years for a variety of skin applications. Several studies have shown that hydrogels with regenerative, antibacterial, and antiinflammatory properties can provide faster and better healing outcomes, particularl...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2023-02-01
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| Series: | European Journal of Histochemistry |
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| Online Access: | https://www.ejh.it/index.php/ejh/article/view/3679 |
| _version_ | 1797895695382872064 |
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| author | Flavia Carton |
| author_facet | Flavia Carton |
| author_sort | Flavia Carton |
| collection | DOAJ |
| description |
Hydrogels based on various polymeric materials have been successfully developed in recent years for a variety of skin applications. Several studies have shown that hydrogels with regenerative, antibacterial, and antiinflammatory properties can provide faster and better healing outcomes, particularly in chronic diseases where the normal physiological healing process is significantly hampered. Various experimental tests are typically performed to assess these materials' ability to promote angiogenesis, re-epithelialization, and the production and maturation of new extracellular matrix. Immunohistochemistry is important in this context because it allows for the visualization of in situ target tissue factors involved in the various stages of wound healing using antibodies labelled with specific markers detectable with different microscopy techniques. This review provides an overview of the various immunohistochemical techniques that have been used in recent years to investigate the efficacy of various types of hydrogels in assisting skin healing processes. The large number of scientific articles published demonstrates immunohistochemistry's significant contribution to the development of engineered biomaterials suitable for treating skin injuries.
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| first_indexed | 2024-04-10T07:29:52Z |
| format | Article |
| id | doaj.art-7b118f45df9d4fed980ee717d81f60a5 |
| institution | Directory Open Access Journal |
| issn | 1121-760X 2038-8306 |
| language | English |
| last_indexed | 2024-04-10T07:29:52Z |
| publishDate | 2023-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | European Journal of Histochemistry |
| spelling | doaj.art-7b118f45df9d4fed980ee717d81f60a52023-02-23T17:46:08ZengPAGEPress PublicationsEuropean Journal of Histochemistry1121-760X2038-83062023-02-0167110.4081/ejh.2023.3679The contribution of immunohistochemistry to the development of hydrogels for skin repair and regenerationFlavia Carton0Department of Health Sciences, University of Piemonte Orientale “A. Avogadro”, Novara Hydrogels based on various polymeric materials have been successfully developed in recent years for a variety of skin applications. Several studies have shown that hydrogels with regenerative, antibacterial, and antiinflammatory properties can provide faster and better healing outcomes, particularly in chronic diseases where the normal physiological healing process is significantly hampered. Various experimental tests are typically performed to assess these materials' ability to promote angiogenesis, re-epithelialization, and the production and maturation of new extracellular matrix. Immunohistochemistry is important in this context because it allows for the visualization of in situ target tissue factors involved in the various stages of wound healing using antibodies labelled with specific markers detectable with different microscopy techniques. This review provides an overview of the various immunohistochemical techniques that have been used in recent years to investigate the efficacy of various types of hydrogels in assisting skin healing processes. The large number of scientific articles published demonstrates immunohistochemistry's significant contribution to the development of engineered biomaterials suitable for treating skin injuries. https://www.ejh.it/index.php/ejh/article/view/3679Immunohistochemistryhydrogelshealing biomarkersskin repairskin regeneration |
| spellingShingle | Flavia Carton The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration European Journal of Histochemistry Immunohistochemistry hydrogels healing biomarkers skin repair skin regeneration |
| title | The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| title_full | The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| title_fullStr | The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| title_full_unstemmed | The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| title_short | The contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| title_sort | contribution of immunohistochemistry to the development of hydrogels for skin repair and regeneration |
| topic | Immunohistochemistry hydrogels healing biomarkers skin repair skin regeneration |
| url | https://www.ejh.it/index.php/ejh/article/view/3679 |
| work_keys_str_mv | AT flaviacarton thecontributionofimmunohistochemistrytothedevelopmentofhydrogelsforskinrepairandregeneration AT flaviacarton contributionofimmunohistochemistrytothedevelopmentofhydrogelsforskinrepairandregeneration |