Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study
Sleep disorders (SD) in patients with dementia are very common in clinical practice. The use of antidepressants with hypnotic actions, such as trazodone, plays an important role in these cases. The aim of this study is to present a profile of the use of trazodone in demented patients with SD, as wel...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2011-02-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100010&lng=en&tlng=en |
| _version_ | 1811297439864324096 |
|---|---|
| author | Einstein Francisco Camargos Marcela Basso Pandolfi Marco Polo Dias Freitas Juliana Lima Quintas Juliana de Oliveira Lima Leandra Camapum Miranda Luciano Wanderley Pimentel Patricia Medeiros-Souza |
| author_facet | Einstein Francisco Camargos Marcela Basso Pandolfi Marco Polo Dias Freitas Juliana Lima Quintas Juliana de Oliveira Lima Leandra Camapum Miranda Luciano Wanderley Pimentel Patricia Medeiros-Souza |
| author_sort | Einstein Francisco Camargos |
| collection | DOAJ |
| description | Sleep disorders (SD) in patients with dementia are very common in clinical practice. The use of antidepressants with hypnotic actions, such as trazodone, plays an important role in these cases. The aim of this study is to present a profile of the use of trazodone in demented patients with SD, as well as a review of trazodone hydrochloride in SD. We evaluated 178 elderly patients with Alzheimer's disease and other dementias, clinically presenting SD and treated with hypnosedative medications. In the one-year period comprising the study, 68 (38.2%) of the 178 had sleep disorders. Most patients (114; 64%) had a diagnosis of Alzheimer's disease. Approximately 85% of patients with SD used hypnosedative drugs. Trazodone was the most commonly used drug among patients (N = 35), with an effectiveness of 65.7%. Trazodone has been shown to be a good option for treatment of the elderly with dementia and associated SD. |
| first_indexed | 2024-04-13T06:05:12Z |
| format | Article |
| id | doaj.art-7b125394370a42b5a5a94f2a100537c9 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-13T06:05:12Z |
| publishDate | 2011-02-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-7b125394370a42b5a5a94f2a100537c92022-12-22T02:59:18ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272011-02-01691444910.1590/S0004-282X2011000100010S0004-282X2011000100010Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review studyEinstein Francisco Camargos0Marcela Basso Pandolfi1Marco Polo Dias Freitas2Juliana Lima Quintas3Juliana de Oliveira Lima4Leandra Camapum Miranda5Luciano Wanderley Pimentel6Patricia Medeiros-Souza7Universidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaUniversidade de BrasíliaSleep disorders (SD) in patients with dementia are very common in clinical practice. The use of antidepressants with hypnotic actions, such as trazodone, plays an important role in these cases. The aim of this study is to present a profile of the use of trazodone in demented patients with SD, as well as a review of trazodone hydrochloride in SD. We evaluated 178 elderly patients with Alzheimer's disease and other dementias, clinically presenting SD and treated with hypnosedative medications. In the one-year period comprising the study, 68 (38.2%) of the 178 had sleep disorders. Most patients (114; 64%) had a diagnosis of Alzheimer's disease. Approximately 85% of patients with SD used hypnosedative drugs. Trazodone was the most commonly used drug among patients (N = 35), with an effectiveness of 65.7%. Trazodone has been shown to be a good option for treatment of the elderly with dementia and associated SD.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100010&lng=en&tlng=ensonodemênciadoença de Alzheimertrazodonaantidepressivos |
| spellingShingle | Einstein Francisco Camargos Marcela Basso Pandolfi Marco Polo Dias Freitas Juliana Lima Quintas Juliana de Oliveira Lima Leandra Camapum Miranda Luciano Wanderley Pimentel Patricia Medeiros-Souza Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study Arquivos de Neuro-Psiquiatria sono demência doença de Alzheimer trazodona antidepressivos |
| title | Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study |
| title_full | Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study |
| title_fullStr | Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study |
| title_full_unstemmed | Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study |
| title_short | Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study |
| title_sort | trazodone for the treatment of sleep disorders in dementia an open label observational and review study |
| topic | sono demência doença de Alzheimer trazodona antidepressivos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100010&lng=en&tlng=en |
| work_keys_str_mv | AT einsteinfranciscocamargos trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT marcelabassopandolfi trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT marcopolodiasfreitas trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT julianalimaquintas trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT julianadeoliveiralima trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT leandracamapummiranda trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT lucianowanderleypimentel trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy AT patriciamedeirossouza trazodoneforthetreatmentofsleepdisordersindementiaanopenlabelobservationalandreviewstudy |