An Upstream Finite Volume Scheme for a Bone Healing Model

This paper is devoted to the introduction of a numerical scheme for a bone healing model and simulation of skull fractures. The mathematical model describes the evolution of mesenchymal stem cells, osteoblasts, bone matrix and osteogenic growth factor. We propose a numerical scheme based on an impli...

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Main Authors: Alexandre Uzureau, Yves Coudiere, Mazen Saad
Format: Article
Language:English
Published: Bulgarian Academy of Sciences, Institute of Mathematics and Informatics 2012-09-01
Series:Biomath
Subjects:
Online Access:http://www.biomathforum.org/biomath/index.php/biomath/article/view/14
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author Alexandre Uzureau
Yves Coudiere
Mazen Saad
author_facet Alexandre Uzureau
Yves Coudiere
Mazen Saad
author_sort Alexandre Uzureau
collection DOAJ
description This paper is devoted to the introduction of a numerical scheme for a bone healing model and simulation of skull fractures. The mathematical model describes the evolution of mesenchymal stem cells, osteoblasts, bone matrix and osteogenic growth factor. We propose a numerical scheme based on an implicit finite volume method constructed on an orthogonal mesh. The efficiency and robustness of the scheme are shown in simulating a skull fracture in rats.
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spelling doaj.art-7b19daee1c7e4f819f1512954cbc4c312023-09-02T21:12:21ZengBulgarian Academy of Sciences, Institute of Mathematics and InformaticsBiomath1314-684X1314-72182012-09-011110.11145/j.biomath.2012.09.25412An Upstream Finite Volume Scheme for a Bone Healing ModelAlexandre Uzureau0Yves CoudiereMazen SaadUniversité de NantesThis paper is devoted to the introduction of a numerical scheme for a bone healing model and simulation of skull fractures. The mathematical model describes the evolution of mesenchymal stem cells, osteoblasts, bone matrix and osteogenic growth factor. We propose a numerical scheme based on an implicit finite volume method constructed on an orthogonal mesh. The efficiency and robustness of the scheme are shown in simulating a skull fracture in rats.http://www.biomathforum.org/biomath/index.php/biomath/article/view/14bone growthfinite volume methodnumerical simulation
spellingShingle Alexandre Uzureau
Yves Coudiere
Mazen Saad
An Upstream Finite Volume Scheme for a Bone Healing Model
Biomath
bone growth
finite volume method
numerical simulation
title An Upstream Finite Volume Scheme for a Bone Healing Model
title_full An Upstream Finite Volume Scheme for a Bone Healing Model
title_fullStr An Upstream Finite Volume Scheme for a Bone Healing Model
title_full_unstemmed An Upstream Finite Volume Scheme for a Bone Healing Model
title_short An Upstream Finite Volume Scheme for a Bone Healing Model
title_sort upstream finite volume scheme for a bone healing model
topic bone growth
finite volume method
numerical simulation
url http://www.biomathforum.org/biomath/index.php/biomath/article/view/14
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